Cartilage and Collagen

Question 1

Name 4 types of cartilage?

Answer 1

1. Fibrocartilage
2. Articular (hyaline) cartilage
3. Elastic cartilage (trachea)
4. Epiphyseal cartilage

Question 2

Key transcription factor for cartilage differentiation?

Answer 2

SOX-9

Question 3

Fibrocartilage cartilage type and example?

Answer 3

1

Tendon/ligament junction with bone

Question 4

Healing response to articular cartilage damage?

Answer 4

Fibrocartilage

Question 5

Elastic cartilage main collagen and example?

Answer 5

Type 2 collagen

Ear

Question 6

Zones of epiphyseal cartilage?

Answer 6

1. Resting zone
2. Proliferating zone
3. Hypertrophic zone
4. Spongiosum
5. Groove of ranvier
6. La croix

Question 7

Type 3 collagen found in? 2

Answer 7

Skin and blood vessels

Question 8

Function of type XI collagen?

Answer 8

Superglue - holds the collagen lattice together in cartilage

Question 9

Type X collagen produced by?

Answer 9

Hypertrophic chondrocytes during enchondral ossification

Question 10

Type X collagen function?

Answer 10

Ossification of the cartilage

Question 11

Type V, VI, IX Collagen occur in small amounts where>

Answer 11

Articular cartilage

Question 12

2 alpha 1 and 1 alpha 2 chains of collagen combine to form?

Answer 12

Procollagen

Question 13

Procollagen is processed and expressed from Golgi apparatus as?

Answer 13

Tropocollagen

Question 14

Multiple collagen fibrils combine to form?

Answer 14

Collagen fibre