Cirrhosis

Question 1

Risk factors for cirrhosis? 7

Answer 1

Can be caused by hepatitis C infection, alcohol-induced liver disease, nonalcoholic fatty liver disease, autoimmune hep, toxins, Prolonged bil obstruction, idiopathic

Question 2

What is Cirrhosis?

Answer 2

Irreversible inflammatory fibrotic liver disease

Question 3

Patho of cirrhosis 5 leading to each other

Answer 3

Necrosis-fibrosis-structure change-hepatic insufficiency-liver fail

Question 4

Manifestations of cirrhosis 10

Answer 4

Jaundice, skin legions, hematic problems, endocrine problems, peripheral neuropathy, hepatic encephalopathy, spider angioma, mm wasting, dilated vessels, ascites, fatigue, pruritus

Question 5

Why skin legions with cirrhosis?

Answer 5

increase in estrogen because the liver can’t metabolize steroid hormones.

Question 6

What/why heme problems with c?

Answer 6

Blood penia because of back up into spleen and annemia coagulation problems because liver can’t make clotting factors any more.

Question 7

Complications of liver fail and portal HTN 4

Answer 7

Bleeding gastric and esophageal varices, edema. liver cancer, spontaneous bacterial peritonitis

Question 8

Why Ascites?

Med term??

Answer 8

Lack of albumin

Colloidal oncotic pressure

Question 9

hepatic Encephalopathy manifestations 6

Answer 9

asterixis, hyperventilation, hypothermia, apraxia, tongue fasciculations, fector hepaticas

Question 10

care for encephalopathy 4

Answer 10

lactulose, antibiotics, lower protein intake, gi bleeds

Question 11

Hepatorenal syndrome Manifestations

Answer 11

azotemia, oliguria, intractable ascites

Question 12

What is the most life threatening complication of cirrhosis?

Answer 12

Varicosities hemorrhage

Question 13

Where does edema go?2

Answer 13

Sacrum and ankles

Question 14

Why ascites and what type of fluid? 3

Answer 14

serous fluid.

Lymph cant get rid of prots and water, hyperaldosternoism, and adh

Question 15

Complications from ascites 3

Answer 15

Hypovolemia, bacterial peritonitis, e. coli (after hem) respiratory complications

Question 16

Important test for varices

Answer 16

EGD

Question 17

Care for encephalopathy 6

Answer 17

Pneumonis, DVT. ulcers, Semi fowlers, plural effussions,oral hygiene (Stomatitis)

Question 18

Paracentesis

Answer 18

removes fluid

Question 19

Liver enzymes 4

Answer 19

Alkaline phosphatase (ALP).
Alanine transaminase (ALT).
Aspartate transaminase (AST).
Gamma-glutamyl transferase (GGT).