Retroviridae

Question 1

Retrovirus

Answer 1

Reverse transcriptase enzyme
Immunosuppressive, cancer
Three layer structure
Genes gag pol env

Question 2

Avian leucosis complex

Answer 2

Rep competent virus
Diff type of symptomes like

Lymphoid leucosis

Osteopetrosis

Renal tumour

Lymphoid leucosis

Affects lymphoblasts that express b lymphocytes
Nodules on bursa spread through metastasis

Osteopetrosis

Osteoblasts affectd

Renal tumour
Nephroblastoma
Carcinoma

Question 3

Replucation defective

Answer 3

Erythriblastosis
V.erb gene
Two forms proliferative aneamic

Myeloblastosis
Target myeloblasts in bone marrow
Leukeamia
Liver enlargement

Sarcoma
Hemagioma in skin
Blood blister
Encourage cannibalism

Question 4

Diagnosis

Answer 4

Clinical signs
Intravenous inoculation chick embryo

Virus detection by cofal test

Novaccination

Question 5

Visna or maedi

Answer 5

Ovine progressive pneumonia
Montana sheep disease

Maedi

1 weightloss
Dyspnoe
Rhythmic head jerking

Lesion only inLungs

Lungs consolidation
Ribimpression

Question 6

Visna

Answer 6

Posterior pareisis leads to paraplegia
Only histopatho lesions
Demyelination of spinal cord

Question 7

Diagnosis

Answer 7

Isolation in blood leucocyte culture

Synctitia
Rounding and giant cell formation

Question 8

Bovine infectious aneamia

Answer 8

Swamp fever
Stomyxs flies

Macrophage replication lifelong viremia

Acute subacute chronic

Vasculitis and glomeerulonephritis

Diagnosis

Coggin test positive confirm by western blotting