What is hypersensitivity?
Immune response causing collateral damage
Allergic and autoimmune responses are example of what?
What mediates Type I hypersensitivity reactions?
Allergy involves reactions to ___ substances.
What name is given to harmless substances which cause allergic reactions?
Type I reactions tend to occur ___.
Type I allergies tend to be (immediate / delayed) and (consistent / unpredictable).
Name an antigen-presenting cell which involved in Type I allergic responses.
Which cells produce the antibodies responsible for mediating Type I hypersensitivity reactions?
(also memory B cells)
What is urticaria?
i.e big red lumpy rashes
How long does urticaria typically last?
How can a Type I allergy be diagnosed?
Serum IgE test
Skin prick / patch testing
What is the jist of Type IV hypersensitivity reactions?
What mediates Type IV hypersensitivity reactions?
Name an example of Type IV hypersensitivity reactions.
Allergic contact dermatitis
How long after exposure to allergens do Type IV hypersensitivity reactions start?
24 - 48 hours
Give an example of a substance which causes a Type IV hypersensitivity reaction.
Thiuram (used in rubber gloves)
Colophany used in adhesives
stuff in tattoos
How can Type IV hypersensitivity be diagnosed?
Nappy rash and excessive handwashing are examples of which type of dermatitis?
Irritant contact dermatitis
Is irritant contact dermatitis an example of hypersensitivity?
not an immune response
Dermatitis can be caused by allergens, irritants or ___.
infection e.g fungal