Which structure joins the epidermis and the dermis?
Dermo-epidermal junction (DEJ)
What are the two layers of the dermo-epidermal junction?
comprised of connective tissue
What are the main cell types found in the dermis?
Immune cells - macrophages, mast cells, lymphocytes, Langerhans cells
Which types of connective tissue fibres are found in the dermis?
How does blood reach the dermis?
Superficial and deep vascular plexuses
What are benign vascular endothelial tumours called?
Apart from arterioles and venules, what other vessels are found in the dermis?
Which cells take antigens to lymphatics in the dermis?
If lymphatic vessels are damaged, what symptom can present?
Which type of nerve provides feeling for the dermis?
Somatic sensory nerves
What are Pacinian corpuscles responsible for sensing?
(23/12 - P is not for pressure, it turns out)
What are Meissner's corpuscles responsible for sensing?
Apart from somatic sensory nerves, which other type of nerves supply blood vessels, nerves and glands in the dermis?
Autonomic nerves - sympathetic and parasympathetic
What do Pacinian corpuscles look like under the microscope?
What is a benign nerve tumour of the skin called?
Which genetic skin condition sees the development of loads of neurofibromas all over the back and other surfaces?
Neurofibromatosis Type 1
What are the three types of glands found in the skin?
What is the function of sebaceous glands?
Secrete sebum into the pilary canal to lubricate hairs and protect from fungal infection
What skin disease involves blocking of pilary canals by excess sebum +/- bacterial colonisation?
What is the function of apocrine glands and where are they found?
Produce oily, odorous fluid
Found in the axillae and perineum
What is the function of eccrine glands and where in particular are they found?
Secrete sweat to cool body by evaporation and moisten palms/soles
Found everywhere, but palms, soles and axillae in particular
Which autonomic nerves supply eccrine glands?