5: Skin structure & function 3 Flashcards Preview

Dermatology Week 1 2017/18 > 5: Skin structure & function 3 > Flashcards

Flashcards in 5: Skin structure & function 3 Deck (22)
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1

Which structure joins the epidermis and the dermis?

Dermo-epidermal junction (DEJ)

2

What are the two layers of the dermo-epidermal junction?

Lamina lucida

Lamina densa

comprised of connective tissue

3

What are the main cell types found in the dermis?

Fibroblasts

Immune cells - macrophages, mast cells, lymphocytes, Langerhans cells

4

Which types of connective tissue fibres are found in the dermis?

Collagen

Elastin

5

How does blood reach the dermis?

Superficial and deep vascular plexuses

6

What are benign vascular endothelial tumours called?

Angiomas

7

Apart from arterioles and venules, what other vessels are found in the dermis?

Lymphatic vessels

8

Which cells take antigens to lymphatics in the dermis?

Langerhans cells

Lymphocytes

9

If lymphatic vessels are damaged, what symptom can present?

Lymphoedema

10

Which type of nerve provides feeling for the dermis?

Somatic sensory nerves

11

What are Pacinian corpuscles responsible for sensing?

Vibration

(23/12 - P is not for pressure, it turns out)

12

What are Meissner's corpuscles responsible for sensing?

Pressure

Light touch

13

Apart from somatic sensory nerves, which other type of nerves supply blood vessels, nerves and glands in the dermis?

Autonomic nerves - sympathetic and parasympathetic

14

What do Pacinian corpuscles look like under the microscope?

Onions

15

What is a benign nerve tumour of the skin called?

Neurofibroma

16

Which genetic skin condition sees the development of loads of neurofibromas all over the back and other surfaces?

Neurofibromatosis Type 1

17

What are the three types of glands found in the skin?

Sebaceous glands

Apocrine glands

Eccrine glands

18

What is the function of sebaceous glands?

Secrete sebum into the pilary canal to lubricate hairs and protect from fungal infection

19

What skin disease involves blocking of pilary canals by excess sebum +/- bacterial colonisation?

Acne

20

What is the function of apocrine glands and where are they found?

Produce oily, odorous fluid

Found in the axillae and perineum

21

What is the function of eccrine glands and where in particular are they found?

Secrete sweat to cool body by evaporation and moisten palms/soles

Found everywhere, but palms, soles and axillae in particular

22

Which autonomic nerves supply eccrine glands?

Sympathetic nerves