2: Skin structure & function 1 Flashcards Preview

Dermatology Week 1 2017/18 > 2: Skin structure & function 1 > Flashcards

Flashcards in 2: Skin structure & function 1 Deck (23)
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1

What is the outer layer of skin called?

Epidermis

2

What kind of cells make up the epidermis?

Stratified squamous epithelium

also known as keratinocytes

3

Which layer of skin is made up of stratified squamous epithelium?

Epidermis

4

Which layer of skin is found beneath the epidermis?

Dermis

5

What kind of tissue makes up the dermis?

Connective tissue

6

Which single layer of cells is formed by the ectoderm before they are cast off?

Periderm

7

Which germ layer turns into the epidermis?

Ectoderm

8

Which germ layer turns into the dermis?

Mesoderm

9

Which cells, found in skin, produce pigmentation?

Melanocytes

10

What are Blaschko's lines?

Developmental growth patterns of skin (not the same as dermatomes)

11

What name is given to accessory parts of the skin found in the dermis?

Appendages

Examples: nails, hair, glands

12

What anchors the skin to bones and allows it to move around?

Subcutaneous fat

13

Which cells make up 95% of the epidermis?

Keratinocytes

14

What are the four epidermal layers?

Keratin layer (lots of keratinocytes with little to no nuclei)

Granular layer

Prickle cell layer

Basal cell layer

15

Which substance is found at the surface of the skin and protects it from damage?

Keratin

16

What does psoriasis look like?

Patches of red crusty skin covered in silver scales

 

17

Where is psoriasis most commonly found on the body?

Scalp

Elbows

Lower back

Knees

18

Why does psoriasis produce crusty scales on the surface of the skin?

Increased cell turnover (around 7 days as opposed to 28)

Lack of proper differentiation

19

What connects cells together in the prickle cell layer?

Desmosomes

20

In which layer of the epidermis do cells lose their nuclei?

Granular layer

21

What are corneocytes?

Terminally differentiated keratinocytes

22

Name three specialised cells found in the epidermis.

What are their functions?

Melanocytes (produce pigment)

Langerhans cells (immune surveillance)

Merkel cells (mechanoreceptors)

23

Give an example of a disease which affects melanocytes.

Vitiligo

Albinism

Malignant melanoma