Scleroderma Flashcards
Systemic Sclerosis involves what systems?
-skin and other body systems
what happens in Systemic Sclerosis?
=Inflamed tissue becomes hardened/ sclerotic
–>May involve kidneys (leading cause of death), lungs and vessels
Systemic Sclerosis is -Chronic, inflammatory, autoimmune ____ _____ disorder
connective tissue
Limited Cutaneous SSc occurs where?
legs, forearms, head
crest syndrome is associated with
Limited Cutaneous SSc
crest syndrome is
- calcium deposits in skin
- raynaud’s
- esophageal dysfunction: acid reflux
- sclerodactyly = thickening and hardening of the skin
- telangiectasias = dilation of capillaries on skin causing red spider veins
2 types of SSC
limited cutaneous= legs, forearms, head
diffuse = all over
assessment for SSC
- Joint pain
- Joint stiffness
- Pitting edema of hands, fingers and forearms
- ->Edema may progress
- Shiny skin
- Taut/ no wrinkles
Diffuse SSC s/s skin/rom:
- Tightening of skin
- Hardening of skin
- Thickening of skin
- Loss of elasticity
- Loss of Range of Motion
- Ulcerations
- Joint contractures
- -> complete loss of function
Diffuse SSC organi involvemnt
- GI
- CV
- Lung
- Renal impairment
GI SSC involvement will see
Esophageal dysmotility Dysphagia Hiatal hernia Esophagitis Decreased Peristalsis Malabsorption/ Diarrhea
CV SSC involvement will see
Raynaud’s
Digit necrosis/ Autoamputation of distal digits
Lung involvement in SSC will see
Pulmonary arterial hypertension
diagnostics for SSC
Similar to SLE
Response to medications helps to distinguish
Clinical presentation
pharmacology for SSC
Steroids & Immunosuppressants
Medications targeting organ disfunction
