Metabolism 06 Flashcards
1
Q
Physiological conditions that favor fatty acid biosynthesis (fed or fasted)
A
fed
2
Q
Identify the hormones that activate and inhibit acetyl CoA carboxylase which is the rate limiting in fatty acid biosynthesis
A
Fasted - acetyl coA carboxylase is inhibited (glucagon and epinephrine)
Fed - acetyl CoA carboxylase is promoted (insulin)
3
Q
What is the rate limiting step in fatty acid biosynthesis
A
Acetyl CoA carboxylase
4
Q
What is the allosteric activator of acetyl coA carboxylase
A
Citrate
5
Q
Allosteric inhibitor of acetyl coA carboxylase
A
Palmitoyl coA
6
Q
What cofactor does acetyl coA carboxylase require
A
Biotin
7
Q
What is the product of acetyl CoA carboxylase
A
Malonyl coA - this is the only inhibitor of FA oxidation
