M3: L-8 Flashcards

1
Q

For what substitution reaction mechanism is a good leaving group more important?

A

SN1

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2
Q

What conditions are used to create better leaving groups from OH and OR electrophiles?

A

acidic conditions ( pronation)

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3
Q

For which substitution reaction mechanism is having a nucleophile more important?

A

SN2

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4
Q

What are the ideal solvent conditions for SN1 reaction mechanisms?

A
  • polar

- able to H bond

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5
Q

What are the ideal solvent conditions for SN2 reaction mechanisms?

A
  • Not able to H bond
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6
Q

What determines which elimination reaction mechanism occurs?

A

Base strength ( strong base = E2) (weak base = E1)

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7
Q

Explain the E1 reaction mechanism:

A
  1. Electrophile leaves and generates a carbocation intermediate
  2. A base (H20 most abundant) removes H+ to form C=C
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8
Q

What controls the ratio of E1: SN1 reactions occurring

A

Relative rates of the two alternative fast steps

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9
Q

Explain the E2 reaction mechanism:

A

The electrophile leaves at the same time the base takes the H+

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