1.16 Haemoglobin Flashcards
1
Q
Draw Haem
A
2
Q
How many oxygens does Haem bind?
A
4
3
Q
Give the importance of CO with haem
A
CO has 200-300x higher affinity to haem than oxygen
4
Q
Draw the rate-limiting step of haem synthesis
- Where does this occur?
A
- Mitochondria
5
Q
Draw the pathway of ALA → Porphobilinogen
- Where does this occur?
A
- Cytoplasm
6
Q
Draw the pathway from PB → Haemoglobin
A
7
Q
What is the composition of haemoglobin?
A
- 4 haem
- 4 Polypeptide
8
Q
Regulation of Haem synthesis
A
(In rate-limiting step)
