1.8 The pentose phosphate pathway Flashcards Preview

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Flashcards in 1.8 The pentose phosphate pathway Deck (14)
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1
Q

Give the steps of the pentose phosphate pathway

A
  1. Glucose-6-Phosphate
  2. 6-Phosphogluconolactone
  3. 6-Phosphogluconate
  4. 6-Phospho-3-ketogluconate
  5. Ribulose-5-phosphate
  6. Ribose-5-phosphate
  7. Fructose-6-phosphate
  8. (Glucose-6-phosphate)
2
Q

Draw the PPP

A
3
Q
A
  • Glucose-6-phosphate dehydrogenase
  • NADP+ → NADPH + H+
4
Q
A
  • Lactonase
  • H2O →
5
Q
A
  • 6-phosphogluconate dehydrogenase
  • NADP+ → NADPH + H+
6
Q
A
  • No enzyme
  • → CO2
7
Q
A

Phosphopentose isomerase

8
Q
A

Transaldolase/Transketolase

9
Q
A

Phosphohexose isomerase

10
Q
A
  • Hexokinase
  • ATP → ADP
11
Q

Indicate the oxidative/non-oxidative parts of the pentose phosphate pathway

A
12
Q

Location of the pentose phosphate pathway

A

Cytoplasm of every cell

13
Q

Give the importance of the pentose phosphate pathway

A
  1. Generate reducing equivalents in the form of NADPH + H+
  2. Provide cells with Ribose-5-phosphate for nucleotides
  3. Rearrange carbon skeletons of dietary carbohydrates
14
Q

How is pentose phosphate pathway regulated

A

Glucose-6-phosphate dehydrogenase

  • NADP+ Activates
  • NADPH + H+ Inhibits