Awesome brain Flashcards

1
Q

how many people in uk affected by neuro-disorder

A

1 in 6

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2
Q

what are neurons senstitive to

A

lack of oxygen and toxic aggregate proteins- mostly cant regenerate

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3
Q

what does grey matter do

A

processing

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4
Q

what is found in grey matter

A

neurons, synapses and processes

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5
Q

what does white matter do

A

communication

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6
Q

what is found in white matter

A

nerve fibres with myelin sheaths

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7
Q

what are the planes in the cns

A

sagittal, coronal, horizontal

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8
Q

what are the central nervous system directions

A

rostral caudal axis with ventral and dorsal

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9
Q

what is localisation of function

A

certain functions have certain locations
the regions communicate to work effectively (white matter important!!)

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10
Q

what is the internal capsule

A

a white matter bundle, connecting motor cortex with spinal cord.
Primary motor cortex sends white matter through the internal capsule, where most crosses the spinal cord.

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11
Q

two outcomes of stroke at the internal capsule

A

paralysis
rigid and hyperflex

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12
Q

outcomes of stroke with pure corticospinal tract lesion or small lesions in motor cortex

A

paralysis or flaccid

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13
Q

how do you treat stroke

A

CT- HEAMORRHAGE OR CLOT?
within 3-5 hours after symptoms
clot busters- tpa or tnk
thrombectomy

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14
Q

what is neurplasticity

A

when nervous system can be modified by experience, behaviour or neural changes
changing connections and the strength of connections
stronger/ weaker or more/ less synapses

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15
Q

what is functional plasticity

A

repurposing neurons after gross injury or loss of brain tissue early in life

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16
Q

examples of induced plasticity changes after stroke

A

robot assisted training
mirror therapy
contralateral restraint

17
Q

what is constraint induced movement therapy used for

A

cerebral palsy- improves movement and induces plasticity in cerebral cortex

18
Q

what is mirror thrpay used for

A

phantom limb pain (unilateral)
hemiparesis
spastic hemiparetic cerebral palsy

19
Q

treatment for parkinsons

A

deep brain stimulation
L-DOPA

20
Q

how is parkinsons and basal ganglia related

A

basal ganglia usually inhibits thalamus
without dopamine causes basal ganglia lesions
xs inhibitory synaptic output to thalamus
causes paucity of movement, increase tone, tremor

21
Q

what are mirror neurons

A

neuron that fires both when an animal acts and when the animal observes the same action performed by another.
activates same pathway in observation and doing