Muscular drugs

Question 1

what does acetylcholinesterase do?

Answer 1

breaks down acetylcholine

Question 2

myopathies

Answer 2

disorders of muscles

Question 3

neuromuscular blockers function

Answer 3

produce paralysis by disrupting the transmission of nerve impulses

Question 4

skeletal muscle spasmolytics function

Answer 4

reduce muscle spasms

Question 5

inflammation

Answer 5

normal response of living tissue to injury, infection, or irritation, involves vascular changes and release of chemicals that help the body destroy harmful agents at the injury site

Question 6

what are the two types of anti-inflammatory drugs?

Answer 6

steroidal and nonsteroidal

Question 7

what do neuromuscular blockers cause?

Answer 7

no analgesia (ability to feel pain), no sedation, need to give positive pressure ventilation

Question 8

competitive non-depolarizers

Answer 8

drugs that block activity at the neuromuscular junction, inhibit effects of ACh

Question 9

what is a common adverse effect among competitive non-depolarizers?

Answer 9

increased blood pressure/ heart rate

Question 10

antidotes

Answer 10

substances given to counteract the effects of another drug

Question 11

what drugs are antidotes?

Answer 11

neostigmine, pyridostigmine, edrophonium

Question 12

how do antidotes work?

Answer 12

bring more ACh into muscle site, reverse the paralyzing effects of competitive non-depolarizers

Question 13

depolarizing drug

Answer 13

muscle paralyzing drugs that depolarize the cell membrane of muscle fibers by mimicking the action of ACh

Question 14

what is an example of a depolarizing drug?

Answer 14

Succinylcholine

Question 15

what drug doesn’t need an antidote because of how fast it works?

Answer 15

Succinylcholine

Question 16

spasmolytics

Answer 16

drug used to treat acute episodes of muscle spasticity associated with neurological and musculoskeletal disorders

Question 17

what does spasmolytics treat?

Answer 17

malignant hyperthermia, equine post anesthetic myositis, traumatic injury that results in muscle spasms

Question 18

what drugs are classified as spasmolytics?

Answer 18

Methocarbamol (treats inflammatory and traumatic conditions), Guaifenesin (muscle relaxant), Diazepam (centrally acting muscle relaxant), dantrolene (peripherally acting muscle relaxant)