Physiology - female reproductive physiology Flashcards

1
Q

what are the main female sex hormones

a.oestrogen and progesterone
b.LH and FSH
c.oestrogen and FSH
d.progesterone and LH

A

a.oestrogen and progesterone

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2
Q

oogenesis

A

formation of female gametes

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3
Q

when does maturation of oocytes from their primitive progenitor begin

a.pre birth
b.birth
c.childhood
d.adolescence

A

a.pre birth

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4
Q

what happens in the initial stage of oogenesis

a.oogonia undergo mitosis to multiply numbers of potential oocytes

b.pre birth oogonia start the 1st meiotic division to form primary oocytes

c.at puberty meiosis 1 is done to form a secondary oocyte

A

a.oogonia undergo mitosis to multiply numbers of potential oocytes

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5
Q

when does meiosis 2 begin with the secondary oocyte

a.pre birth

b. puberty

c.fertilisation

A

b. puberty

it is ovulated along with first polar body

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6
Q

a secondary oocyte is

a.haploid
b.diploid

A

a.haploid

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7
Q

a primary oocyte is

a.haploid
b.diploid

A

b.diploid

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8
Q

at which point does meiosis 2 resume and the secondary oocyte splits into the ovum and the second polar body

a.pre birth
b.puberty
c.fertilisation

A

c.fertilisation

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9
Q

day 1-14 of the ovarian cycle is known as which phase

a.follicular
b.luteal

A

a.follicular

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10
Q

at birth where are the primary oocytes stored

a. follicles
b.cells
c.ovaries
d. lobules

A

a. follicles

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11
Q

what type of follicle is made up of the primary oocyte surrounded by a single layer of cells (granulosa cells) sitting on CT basement membrane

a.primordial
b.primary
c.secondary

A

a.primordial

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12
Q

which type of follicle is made up of multilayered follicular cells , a zone pellucida surrounding the ovum and and a basement membrane around the structure

a.primordial
b.primary
c.secondary
d.tertiary

A

b.primary

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13
Q

which type of follicle is made up of theca cells making up an internal and external surrounding the structure and the formation of antrum inside the cell (cavitation in the granulosa cells)

a.primordial
b.primary
c.secondary
d.tertiary

A

c.secondary

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14
Q

in which type of follicle is the ovum surrounded by a zone pellucida, a cumulus oophurus (COC) with a large antrum present

a.primordial
b.primary
c.secondary
d.tertiary

A

d.tertiary

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15
Q

at which stage does only 1 follicle develop further becoming the dominant follicle

a.between primordial and primary
c.between primary and secondary
d.between secondary and tertiary

A

c.between primary and secondary

the remaining follicle (secondary) is known as the griffian follicle

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16
Q

when does the follicle become large enough to distort the surface of the ovary and rupture releasing the ovum

a.day 10
b.day 12
c.day 14
d.day 16

A

c.day 14

17
Q

what does the follicle fill with following rupture

a.blood
b.lymph
c.mucous
d.proteolytic enzymes

A

a.blood

18
Q

what does the follicle become when it filled with blood

a. corpus luteum
b.corpus haemorrhagicum
c.graffian follicle

A

b.corpus haemorrhagicum

19
Q

what is ovulatory pain due to irritation from the blood in the follicle following rupture entering the peritoneum known as

A

mittleschermz

20
Q

what is the follicle known as when the theca cells swell up and become rich in fatty deposits an the blood vessels infiltrate the follicle (attracted by vascular endothelium growth factor)

a.corpus haemorrhagicum
b.corpus luteum

A

b.corpus luteum

21
Q

when does the corpus luteum breakdown precipitating the breakdown of the uterine wall ( menses)

a.day 14
b.day 10
c.day 24

A

c.day 24

10 days after ovulation

22
Q

what is secreted from the hypothalamus at the start of the menstrual cycle

a.GnRh
b.CRH
c. TRH

A

a.GnRh

gonadotropin releasing hormone

23
Q

after travelling down the hypophyseal portal circulation to anterior pituitary what does GnTH cause the release of ?

a. FSH and LH
b.oestrogen and progesterone

A

a. FSH and LH

24
Q

which hormone encourages cell division and secretion of oestrogen by granulosa cells

a.LH
b.FSH
c.progesterone
d.GnTH

A

b.FSH

25
Q

which hormone functions to form the luteal body as well as stimulating androgen production which diffuse into granulosa cells to be made into oestrogens

a.LH
b.FSH
c.progesterone
d.GnTH

A

a.LH

26
Q

after day 10 what effect does oestrogen have on LH secretion

a.increase
b.decrease

A

a.increase

leads to dramatic surge in LH at day 14 stimulating ovulation

27
Q

surge in which hormone at day 14 leads to ovulation

a.LH
b.FSH
c.progesterone
d.GnTH

A

a.LH

28
Q

at day 14 corpus luteum takes over hormone production and produces oestrogen and progesterone which …………… feedback on LH and FSH

a.negatively
b.positively

A

a.negatively

removes negative feedback on GRH causing it to rise again

29
Q

what is the deep layer of the endometrium of the uterus that is not shed known as

a. stratum functionale
b.stratum basalis

A

b.stratum basalis

30
Q

which arteries supply the deep layer of the uterine endometrium that is not shed

a.basilar
b.spiral

A

a.basilar

31
Q

what is the more superficial layer of the uterine endometrium that alters during the menstrual cycle

a.stratum basalis
b.stratum functionale

A

b.stratum functionale

32
Q

which arteries supply the stratum functionale

a.basilar
b.spiral

A

b.spiral

33
Q

what happens to the endometrial wall in the start of the menstrual cycle

a.2/3 sloughs off leaving just stratum basale

b.thickens and proliferates

c.tests tube glans lengthen without corresponding thickening of uterine walls and become tortuous becoming highly vascularised and filling up with secretions rich in glycogen

A

a.2/3 sloughs off leaving just stratum basale

34
Q

what happens to the endometrial wall day 1-14 under the influence of oestrogens

a.2/3 sloughs off leaving just stratum basale

b.thickens and proliferates

c.tests tube glans lengthen without corresponding thickening of uterine walls and become tortuous becoming highly vascularised and filling up with secretions rich in glycogen

A

b.thickens and proliferates

35
Q

what happens to the endometrial wall day 14- 28 following ovulation under the control of progesterone

a.2/3 sloughs off leaving just stratum basale

b.thickens and proliferates

c.tests tube glans lengthen without corresponding thickening of uterine walls and become tortuous becoming highly vascularised and filling up with secretions rich in glycogen

A

c.tests tube glans lengthen without corresponding thickening of uterine walls and become tortuous becoming highly vascularised and filling up with secretions rich in glycogen

36
Q

atresia of the corpus lute following no fertilisation of an ovulated ovum leads to a rapid………… in hormone levels at day 24

a.rise
b.fall

A

b.fall

leads to ischameia and infarction of endometrium which sloughs off and is shed during the menstrual flow

37
Q

what hormone promotes deposition of fat around the hips, high vocal range , and mammary duct development

a.LH
b.FSH
c.progesterone
d.GnTH
e.oestrogen

A

e.oestrogen

38
Q

what hormone promotes the formation of secretory lobules in the breast

a.LH
b.FSH
c.progesterone
d.GnTH
e.oestrogen

A

c.progesterone