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semester 1: ccp > Ventilation Pharmacology Anesthetics and Sedatives > Flashcards

Ventilation Pharmacology Anesthetics and Sedatives Flashcards

1
Q

Ketamine exerts its sedative and anesthetic effects through which of the following?

A

Ketamine exerts its sedative and anesthetic effects through which of the following?

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2
Q

Which of the following IV anesthetics demonstrates preservation of response to respiratory stimuli?

A

Ketamine

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3
Q

Which of the following is a consequence of Ketamine’s action on Calcium movement?

A

Bronchodilation

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4
Q

Propofol has the lowest volume of distribution of any induction agent.
True or False?

A

False

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5
Q

Which of the following IV aesthetics are metabolized hepatically by the
CYP450 system? Select ALL that apply.

A

Dexmedetomidine
Ketamine
Propofol

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6
Q

Propofol mechanism of action for sedation is related to GABAA agonism, but
it also shows which of the following non-sedation related effects? Select
ALL that apply.

A

Antiemetic
Anticonvulsant
Impaired Response to Hypoxia and Hypercapnia
Green Urine

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7
Q

Which of the following is true regarding IV aesthetics and their effects on
cardiac contractility?

A

Ketamine exerts negative inotropic effects through its effects on Calcium

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8
Q

Features of PRIS include all of the following, except?

A

Tachycardia

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9
Q

Midazolam exerts its sedatives effects through agonism of which of the
following GABA receptors?

A

GABAAa

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10
Q

Midazolam has adequate bioavailability in IV, IM, PO, and intranasal
administration. True or False?

A

True

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11
Q

All of the following IV aesthetics preserve airway reflexes, except for:

A

Propofol

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12
Q

When considering effects of the various agents, which of the following is less suitable for patients with increased ICP due to its minimal effects on
cerebral metabolism?

A

Midazolam

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13
Q

Which of the following IV sedatives exerts its effects through alpha 2
agonism?

A

Etomidate

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14
Q

Which of the following is true regarding the pharmacokinetics of Dexmedetomidine?

A

It is both highly lipid and water soluble

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15
Q

Which of the following is true regarding the hemodynamic effects of Dexmedetomidine:

A

Bradycardia with maintained cardiac output due to intact contractility

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16
Q

Which of the following is true regarding the systemic effects of Etomidate?

A

Maintained sympathetic tone and myocardial function
Unaltered pharmacodynamics and pharmacokinetics in
hemorrhagic shock
Reduction in cerebral blood flow and metabolic rate
All choices

17
Q

Etomidate causes which of the following adverse effects:

A

Adrenal cortical inhibition

semester 1: ccp (44 decks)

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