Class IV (Antiarrhytmics) Ca Channel Blockers

Question 1

All of the following are true regarding Calcium channel blockers except:

Answer 1

Act exclusively on L-Type Calcium Channels in smooth muscle

Question 2

Non-Dihydropyridine CCB have high selectivity for vascular smooth muscle.
True or False?

Answer 2

False

Question 3

Which of the following is considered a contraindication to Diltiazem?
Select all that apply.

Answer 3

Administration concomitantly or within a few hours of beta blocking agents

Severe hypotension or cardiogenic shock

All of the options

Second or Third degree AV block without pacemaker

Pregnancy

Question 4

Diltiazem has which of the following effects:
Select all that apply.

Answer 4

Decreased inotrope
Arterial Dilation
Increased effective refractory period in the AV node and myocytes

Question 5

Nifedipine and other Dihydropyridine CCB exert which of the following:

Answer 5

Vascular smooth muscle relaxation

Question 6

Please match the following drug interactions with their adverse outcome:

Answer 6