MEDICATIONS AFFECTING COAGULATION PART 1

Question 1

The following describe how various classes of anticoagulant medications act, except :

Answer 1

Direct activation of factor Xa

Question 2

Please match the following medications with their mechanism of action:

Answer 2

Question 3

Which of the following is true regarding the pharmacokinetics of Warfarin:

Answer 3

Is nearly 99% bound to plasma albumin

Question 4

Warfarin…

Answer 4

Interferes with Vitamin K synthesis

Question 5

Heparin is classified as which of the following:

Answer 5

Activator of anticlotting factors

Question 6

All of the following are true regarding HIT except for:

Answer 6

Type 1 HIT is a severe antibody mediated thrombocytopenia

Question 7

Which of the following is true regarding low molecular weight heparin:

Answer 7

LMWH is only capable of deactivating factor Xa and mild factor Ila

Question 8

Which of the following does not act on factor Xa to inhibit thrombin

Answer 8

Warfarin

Question 9

Which of the following anticoagulants, are currently accepted and well studied, for treatment of cancer related thrombus:

Answer 9

LMWH

Question 10

Select all of the following medications that have strong interactions with DOACs:
Select all that apply.

Answer 10

Certain ABx
Phenytoin
Certain Antiarrythmics
Any Medications that alter CYP metabolic enzymes
Anti-platelet