1. Healthing and Repair

Question 1

Def of repair:

Answer 1

replacement of a damaged tis by a new healthy one

Question 2

______: replacement of injured cells by new PARENCHYMAL cells of the same type by division of adjacent ones

Answer 2

regeneration (restitution)

Question 3

_____: replacement of lost tis by scar formation

Answer 3

organization

Question 4

cells of the body can be divided int 3 groups according to their regenerative capacity

Answer 4

1. labile
2. stable
3. permanent

Question 5

Name (3) labile cells

Answer 5

1. epithelial cells
2. crypt cells of gut mucosa
3. hematopoietic stem cells

Question 6

___ cells normally divide actively throughout life

Answer 6

labile cells

Question 7

___ cells have a long life span–> very slow rate of division

Answer 7

stable cells

Question 8

___ cells remain in intermitotic phase for long periods, retain capacity to enter the mitotic cycle when needed

Answer 8

stable cells

Question 9

__cells can be in the form of ___ cells in solid organs or ___ cells (such as blasts & cytes)

Answer 9

parenchymal

mesenchymal

Question 10

___ will form when the CT framework is destroyed

Answer 10

scar formation

Question 11

Regeneration occurs when ____ parenchymal cells remain & _____ in the area of necrosis

Answer 11

enough viable

INTACT CT framework in the area

Question 12

Nmae 3 permanent cells

Answer 12

Neurons
myocardial cells
skeletal M cells

(they have no capacity for mitotic division in post natal life)

Question 13

Scar tis replaces the tiss in the injured area by ____ tiss

Answer 13

granulation tis

Question 14

4 Things that occur during scar formation

Answer 14

1. replaced of injured area by grandulation tiss
2. loops of cap surrport the myofibroblasts
3. inflam cells
4. actively contracts to reduce wound size

Question 15

3 types of wounds

Answer 15

1. abrasion
2. incision & laceration
3. wounds with epidermal defect

Question 16

_____ wound is the removal of superficial part of epidermis . Regenerate without scaring

Answer 16

abrasion wound

Question 17

Basal cell layer (___ cell) regenerate the epithelium without scaring during abraasion wounds

Answer 17

labile

Question 18

Incision is a ____ wound

Answer 18

cute

Question 19

Laceration is a ___ wound

Answer 19

tearing

Question 20

Both epidermis and dermis are involved during (2) wounds

Answer 20

incision (cut)

laceration (tear)

Question 21

______ would: has rapid healing. There is no infection, no foreign mat. and minimal tis loss

Answer 21

1st intention

Question 22

Wounds with epidermal effect loss large areas of epidermis and has necrosis of underlying dermis. Ex___ & ___

Answer 22

burns and crush injuries

Question 23

_____ intention: is a wound with epidermal defects

Answer 23

2nd intention

Question 24

(5) causes of defective wound healing

Answer 24

1. failure of syn of collagen fibers
2. excessive collagen production
3. local factors
4. Diabetes mellitus
5. Excessive levels of corticosteroids