13 - Liver and Pancreas Dysfunction (part 2) Flashcards Preview

Med Surg P.P.'s > 13 - Liver and Pancreas Dysfunction (part 2) > Flashcards

Flashcards in 13 - Liver and Pancreas Dysfunction (part 2) Deck (12):

Liver is unable to detoxify toxic byproducts of metabolism.  Ammonia is the major etiologic factor of encephalopathy.  Major S/S is asterixis (liver flap), which is flapping tremor of the hands.

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Hepatic Encephalopathy


Large ecchymosis appearing in the flanks as a result of pancreatitis.

a.) Grey Turner's Sign

b.) Cullen's Sign

Grey Turner's Sign

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Increased pressure through portal venous system because of a blockage.  Obstructed blood flow through damaged liver.  Causes GI bleeding (black tarry stool and hematemesis), encephalopathy, coagulopathy, and ascites.

Portal Hypertension

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Systemic, viral infection that causes necrosis and inflammation of liver cells.  Altered liver function.

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Viral Hepatitis

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Autodigestion of the pancreas by pancreatic enzymes.  Cellular destruction and organ damage.  The pancreas eats itself.

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Onset is abrupt.  Early symptoms include fever, chills, rash, arthralgia, pruritus, and anorexia.  Late symptoms include Jaundice, dark urine, and an enlarged/tender liver.  Treatment includes short course of high-dose corticosteroids, rest, small/frequent meals, a low protein, fat, and high carbohydrate diet.  IV fluid containing dextrose as needed.

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Drug Induced Hepatitis

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One of the main S/S of pancreatitis is pain.  

1.) Which specific type of pain?

(3 parts to answer)

Mid epigastric pain, radiating to the midback.  

Pain does not decrease even with vomiting.

Rebound tenderness


What type of diet do you want patients with pancreatitis to have?

Low fat, protein, and high carbohydrate diet.


Backup of venous blood flow from portal HTN.  Failure to metabolize aldosterone.  Accumulation of albumin-rich fluid.

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What are the three main lab values looked at when diagnosing pancreatitis?

Lipase, Amylase, & BMP.

C-reactive protein is elevated


Ecchymosis in the umbilical area as a result of pancreatitis.

a.) Grey Turner's Sign

b.) Cullen's Sign

Cullen's Sign

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Resembles viral hepatitis, but is caused by exposure to toxic chemicals (medications, botanicals, alcohol, and/or industrial chemicals).  Treatment includes removal of the causative agent.  S/S include anorexia, N/V, Jaundice, and hepatomegaly.  There are no effective antidotes, and a delay in treatment can result in increased severity.

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Toxic Hepatitis

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