physiology Flashcards

1
Q

what valves close on S1

A

mitral and tricuspid

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2
Q

what makes a soft S1

A

Mitral regurgitation

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3
Q

what makes a loud S1

A

mitral stenosis // left to right shunt // hyper dynamic

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4
Q

what causes S2

A

aortic and pulmonary valves closing

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5
Q

when is S2 soft

A

aortic regurgitation

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6
Q

fixed S2 split

A

ASD

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7
Q

causes widely split S2

A

deep inspiration, RBBB, pulm stenosis, mitral regurgitation

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8
Q

cause of reversed S2

A

LBBB, severe aortic stenosis, patent ductus arteries

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9
Q

when is S2 loud

A

systemic or pulmonary hypertension // ASD without pulmonary HTN

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10
Q

what is S3

A

diastolic filling of ventricle

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11
Q

when is S3 normal

A

<30

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12
Q

when is S3 abnormal

A

LV failure, constrictive pericarditis, mitral regurgitation

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13
Q

when is S4 heard

A

aortic stenosis, HOCM, HTM

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14
Q

what is pulses paraxodus

A

fall in systolic BP during inspiration –> faint

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15
Q

causes pulses paraxodus

A

asthma, cardiac tamponade

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16
Q

causes slow rising pulse

A

aortic stenosis

17
Q

causes collapsing pulse

A

aortic regurgitation, patent ductus arteriosus, hyperkinetic (anaemia, thyrotoxic, fever)

18
Q

what causes pulses alternates

A

sevrer LVF

19
Q

what causes a jerky pulse

A

HCOM (or bisferiens pulse)

20
Q

when is a non-pulsatile JVP seen

A

SVC obstruction

21
Q

what is kussmauls sign

A

rise in JVP in inspiration of constrictive pericarditis

22
Q

first protein to rise in MI

A

myoglobin

23
Q

what enzyme is good for reinfarction

A

CK-MB

24
Q

when is BNP produced

A

by LV in response to strain

25
Q

causes raised BNP

A

MI< HF, valve disease, CKD (reduced excretion)

26
Q

effects BNP

A

vasodilator, diuretic, suppresses sympathetic + RAAS