skin Flashcards

1
Q

largest organ in the body

A

skin

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2
Q

thickest skin

A

soles of the feet

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3
Q

thinnest skin

A

upper and lower eyelids

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4
Q

dark pigment that protects the epidermis from ultraviolet radiation

A

melanin

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5
Q

sweat is produced by?

A

eccrine glands

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6
Q

serves as personal identification; patterns assumed by ridges and intervening sulci

A

dermatoglyphics

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7
Q

brownish black pigment

A

eumelanin

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8
Q

similar pigment found in red hair

A

pheomelanin

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9
Q

where is melanin synthesized?

A

tyrosine and cystine in the melanosomes

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10
Q

congenital melanin disorder caused by defect in tyrosine

A

albinism

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11
Q

skin pigmentation in affected patches due to decreased activity of melanocyte

A

vitiligo

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12
Q

mediates and contacts allergic response in the skin and delayed hypersensitivity reaction

A

dendritic cells

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13
Q

where are dendritic cells derived from?

A

bone marrow and blood borne cells

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14
Q

responsible for sensory mechanoreceptor

A

merkel cells

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15
Q

where are merkel cells derived?

A

neural crest cells

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16
Q

most superficial layer of the epidermis

A

stratum corneum

17
Q

process of continuously shedding cells

A

desquamation

18
Q

only seen in thick skin; consists of thin translucent layer of extremely flattened eosinophilic cells

A

stratum lucidum

19
Q

3-5 layers of flattened polygonal cells undergoing terminal differentiation

A

stratum granulosum

20
Q

composed of stratum basale and stratum spinosum

A

malphigian layer

21
Q

deepest layer of epidermis; site of active mitosis and contains melanocytes

A

stratum basale

22
Q

tonic receptors for sustained light touch and for sensing an object’s texture

A

merkel cells

23
Q

responds to high and low temperatures, pain, and itching

A

free nerve endings

24
Q

web of sensory fibers surrounding the bases of hair follicles in the reticular dermis

A

root hair plexus

25
Q

initiate impulse when light-touch or low frequency stimuli against skin

A

meissner corpuscle

26
Q

found in penis and clitoris

A

krause end bulbs

27
Q

stimulated by stretch or twisting the skin

A

ruffini corpuscles

28
Q

second most common tumor arising on sun exposed skin

A

squamous cell carcinoma

29
Q

most common invasive cancer in human

A

basal cell carcinoma