unit 8 Flashcards

1
Q

Main hormone product of the testes:

A

Testosterone

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1
Q

Main hormone product of the ovaries:

A

Estradiol
Progesterone

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2
Q

The exception to negative feedback of gonadal steroids at the hypothalamus and anterior pituitary

A

Sustained high levels of estradiol trigger a surge of LH/FSH

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3
Q

Cholesterol- _____ - ______ - _______ - DHT

A

Progesterone
Adione
Testosterones

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4
Q

Why are the testes away from the body?

A

Sperm needs to be 2-3 degrees less warm than the body temperature

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4
Q

What is the condition when testes fail to descend?

A

cryptorchidism

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4
Q

Where is the epididymis located?

A

Above the testes

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4
Q

The journey of sperm from the testes

A

Seminiferous tubules
Epididymis
Vas deferens
Seminal vesicle
urethra

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5
Q

___ cells are located in the interstitium of the seminiferous tubules, the ____ cells are located in the tubule

A

Leydig
Sertoli

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6
Q

Leydig cells make ______

A

Androgens (testosterone)

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7
Q

Sertoli cells ______ spermatogenesis

A

Coordinate

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8
Q

Spermatogonia cells are ____

A

Mitotic

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9
Q

When spermatogonia cells enter meiosis they are called _____ in meiosis 1, _____ in meiosis 2 and _____ when they have completed meiosis but not remodeling

A

Primary spermatocyte
Secondary spermatocyte
spermatid

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10
Q

Primordial follicles have three parts:

A

Oocyte surrounded by a single layer of granulosa cell precursors covered in basal lamina

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11
Q

A primary follicle has an enlarged _____ and the granulosa cells ___________

A

Oocyte
Begin to divide but are still SINGLE LAYER

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12
Q

Secondary follicles develop ____; a layer of cells outside the _________

A

Theca
Basal lamina

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13
Q

The corpus luteum is formed from the ________

A

Ruptured follicle

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14
Q

Primordial follicle - ________ - _________ - _________ - _______ - ________

A

Primary follicle
Secondary follicle
Mature follicle
Ovulated oocyte
Corpus luteum

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15
Q

The surge of _____ causes ovulation

A

LH

16
Q

The rise of estrogen concentration occurs in the _____ phase

A

Proliferative

17
Q

sustained high levels of _____ cause surge of ___

A

estrogen
LH hormone

18
Q

The corpus luteum secretes mainly ______ and some _____ during the _____ phase of the cycle

A

Progesterone
estrogen
Secretory

19
Q

High levels of progesterone and estrogen cause _________ feedback with growth hormones LH and FSH

A

Highly negative

20
Q

The commitment to male or female gonad is regulated by ____ (___________) which is expressed by ______

A

Sry
Master transcription factor
Pre-Sertoli cells

21
Q

When someone lacks Sry they will have ______ gonads

A

Female

22
Q

The duct work of gamete transportation IN MALES is regulated by _________ from _______ that act on the ________ duct and ___________ from _______ which causes regression of _________ duct

A

Testosterone
Leydig cells
wollfian
Anti-mullerian hormone
Sertoli cells
Mullerian

23
Q

The duct work of gamete transportation IN FEMALES is regulated by ______________

A

Lack of testosterone or anti-mullerian hormone, default to female

24
Q

What is the signal to form external female genitalia?

A

Absence of a signal

25
Q

The signal to form MALE external genitalia is ______ from ____ cells which must be in the ____ form

A

Testosterone
Leydig
DHT

26
Q

Individuals that lack the 5a-reductase will prevent ____________ because _______

A

Formation of male external genitalia
Testosterone cannot convert to DHT

27
Q

If a male has loss of function for androgen receptors what will happen?

A

No testes decent
No wollfian ducts
Mullerian ducts retained

28
Q

Stretch of vaginal canal causes signaling through the _____ which causes release of _____ which then stimulates ________

A

CNS
oxytocin
Uterine contractions

29
Q

The parturition has a positive feedback reflex involving _________from the ___________

A

Oxytocin
Posterior pituitary

30
Q

During the parturition there will be cervical _______, rhythmic __________, _____ of baby, _______ of the placenta

A

Softening
Uterine contractions
Delivery
Expulsion

31
Q

Trophectoderm will give rise to ________

A

Extra-embryonic membranes

32
Q

Inner cell mass will give rise to ___________

A

Embryo proper

33
Q

The first differentiated cell types in mammalian embryos are:

A

Inner cell mass
Trophectoderm

34
Q

Fertilization of the egg occurs in the ________

A

Fallopian tube (ova duct)

35
Q

If a male has loss of function for androgen receptors what will happen?

A

No testes decent
No wollfian ducts
Mullerian ducts retained

36
Q

Individuals that lack the 5a-reductase will prevent ____________ because _______

A

Formation of male external genitalia
Testosterone cannot convert to DHT

37
Q

The signal to form MALE external genitalia is ______ from ____ cells which must be in the ____ form

A

Testosterone
Leydig
DHT

38
Q

What is the signal to form external female genitalia?

A

Absence of a signal

39
Q

The duct work of gamete transportation IN FEMALES is regulated by ______________

A

Lack of testosterone or anti-mullerian hormone, default to female

40
Q

The duct work of gamete transportation IN MALES is regulated by _________ from _______ that act on the ________ duct and ___________ from _______ which causes regression of _________ duct

A

Testosterone
Leydig cells
wollfian
Anti-mullerian hormone
Sertoli cells
Mullerian

41
Q

When someone lacks Sry they will have ______ gonads

A

Female

42
Q

The commitment to male or female gonad is regulated by ____ (___________) which is expressed by ______

A

Sry
Master transcription factor
Pre-Sertoli cells