C-10 Flashcards

1
Q

what would you find in the epidermis

A

outermost: oil and salt
granulosum: waterproof keratinized skin
spinosum: dendritic cells and karatinocytes
basale: basal cells and melanocytes

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2
Q

what would you find in the dermis

A

blood vessels
nerve endings
sebaceous glands
hair follicles

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3
Q

what is the tonicity of the skin

A

hypertonic

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4
Q

components of the normal skin flora

A

viruses
yeast
gm+ bacteria

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5
Q

virulence

A

virulence factors help microbes evade the immune system

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6
Q

how would you experimentally determine whether something is a virulence factor

A
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7
Q

pimple

A

when the base of a hair follicle
becomes red, swollen, and filled with pus

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8
Q

stye

A

(staph and eye) AKA hordeolum – when
folliculitis occurs in an eyelash follicle at the base of the eyelid

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9
Q

furuncle

A

(boil) is a larger, more painful
folliculitis that comes from the spread of the infection into surrounding tissues

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10
Q

carbuncle

A

is when several furuncles
coalesce, usually in areas of thicker skin (like the back of the neck). Systemic, deeper infectin – triggers fever and chills

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11
Q

reliable way to spot measles

A

kopek’s spots on oral mucosa

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12
Q

caused by herpes

A

cold sores
genital herpes
chicken pox
shingles

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13
Q

MMR vaccine

A

measles
mumps
rubella
- live attenuated and combination vaccine

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14
Q

papillomaviruses causes

A

warts

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15
Q

good candidate for shingles vaccine

A

60+ that had chicken pox as a child

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16
Q

disease caused my fungus

A

mycoses

17
Q

fungi that cause dermatomycosis

A

dermatophytes

18
Q

ringworm

A

fungus

19
Q

2 fungi in skin

A

Candida albicans and malassezia

20
Q

cutaneous mycoses

A

direct or indirect contact; or when antibiotics kill normal bacterial flora and allow inhabitants to overgrow

21
Q

s. aureus

A

nose
makes coagulase and other enzymes

22
Q

s. epidermidis

A

epidermis

23
Q

disease caused by s. aureus

A

impetigo
scalded skin syndrome
folliculitis
MRSA

24
Q

disease caused by s. pyogenes

A

strep throat
necrotizing facsiitis
impetigo
erysipelas

25
Q

pseudomonas aeruglnosa makes a green pigment called

A

pyocyanin; damages host cells with reactive oxygen species

26
Q

gas gangrene

A

clostridium perfringens (gm+)

clean wound, debride, aggressive IV antibiotics

27
Q

most bacteria found in

A

epidermis along with dendritic cells and dead cells

28
Q

hair follicles and sebaceous glands found in

A

dermis

29
Q

necrotizing diseases

A

necrotizing fasciitis
gas gangrene

30
Q

s. aureus

A

treated with semisynthetic derivative

31
Q

anti-phagocytic virulence factors

A

capsule
slime layer
A and M protein

32
Q

virulence factors that help bacteria invade deeper into the skin

A

enzymes and toxins

33
Q

factors that make pseudomonas aeruginosa a problem when treating burn patients

A
  • lots of virulence factors
  • ubiquitous
  • grow in antiseptics and disinfectants
  • thrive in warm and moist environments