Mood stabilizer Flashcards

1
Q

Which mood stabilizer is used as the first line of tx?

A

lithium

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2
Q

What is lithium effective in tx of?

A
  1. acute mania
  2. acute Bipolar depression
  3. Prevention of manic episodes
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3
Q

How long does it take for lithium to have a full response?

A

3-6 weeks

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4
Q

Are NSAIDS contraindicated with lithium?

A

duh

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5
Q

What is the therapeutic level of lithium?

A

0.5-1.2

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6
Q

what therapeutic level shows signs of early lithium toxicity?

A

1.2-1.5

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7
Q

What therapeutic level shows signs of advanced lithium toxicity?

A

1.5-2

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8
Q

What therapeutic level shows signs of severe lithium toxicity?

A

2+

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9
Q

What are COMMON EXPECTED side effects of lithium?

A
  1. fine hand tremors
  2. polyuria, mild thirst
  3. nausea
  4. weight gain
  5. sedation
  6. acne
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10
Q

Signs of early lithium toxicity

A
  1. N/V/D
  2. slurred speech
  3. Muscle weakness
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11
Q

signs of advanced lithium toxicity

A
  1. Coarse hand tremor
  2. GI upset
  3. Mental confusion
  4. Muscle hyper irritability
  5. EEG changes
  6. incoordination
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12
Q

what is the tx for someone experiencing advanced signs of lithium toxicity?

A

saline bolus

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13
Q

signs of severe lithium toxicity

A
  1. ataxia
  2. serious EEG changes
  3. Blurred vision
  4. Clonic movements, seizures
  5. Stupor
  6. Coma/Death
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14
Q

Long term side effects of lithium

A

HYPOthyroidism
Kidney dysfunction

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