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Antidepressants Flashcards

(36 cards)

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1
Q

What is key with antidepressants?

A

safety safety safety

bc of increased risk of suicide within the first week of taking it

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2
Q

What are the different SSRIs

A
  1. Citalopram
  2. Escitalopram
  3. Fluoxetine
  4. Paroxetine
  5. Sertraline
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3
Q

What are SSRIs useful in tx for?

A
  1. Depression w anxiety
  2. Panic disorder
  3. PTSD
  4. OCD
  5. bulimia
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4
Q

Side effects of SSRIs

A
  1. Sleep disturbance
  2. Sexual dysfunction
  3. Reduced appetite
  4. Rash/SJS
  5. Tension headaches
  6. Hyponatremia
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5
Q

How long does it take SSRIs to take full effect?

A

2-3 weeks for full effect

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6
Q

Symptoms of serotonin syndrome

SHIVERS

A

Shivering
Hyperreflexia
Increased temp
VS instability
Encephalopathy
Restlessness
Sweating

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7
Q

Do SSRIs increase bleeding tendencies?

A

YES

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8
Q

What are the different SNRIs?

A
  1. Venlafaxine
  2. Desvenlafaxine
  3. Duloxetine
  4. Levomilnacipran
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9
Q

Do SSRIs and SNRIs have the same symptoms?

A

yes

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10
Q

What are SNRIs useful in tx for?

A
  1. MDD
  2. anxiety disorder
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11
Q

What are the adverse effects of SNRIs?

A

Serotonin syndrome
Hyponatremia

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12
Q

What is trazodone used for?

A

mainly used for sleep but its an antidepressant

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13
Q

What should be known about trazodone?

A
  1. extremely sedating
  2. CAN be given in adjunct with SSRIs
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14
Q

What is an adverse effect of Trazodone?

A

Priapism

aka painful erect penisssss

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15
Q

What are the different TCAs?

A
  1. Amitriptyline
  2. Doxepin
  3. Imipramine
  4. Nortriptyline
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16
Q

What stimulating effects do TCAs target?

Study These Flashcards
A

Target fatigue and lethargy

17
Q

What sedating effects do TCAs target?

Study These Flashcards
A

target agitation or restlessness

18
Q

What are the anticholinergic side effects of TCAs?

Study These Flashcards
A
  1. Dry Mouth
  2. Blurred vision
  3. Tachycardia
  4. Constipation
  5. Urinary retention
  6. Esophageal reflux
  7. Photophobia
  8. Sexual dysfunction
19
Q

What two anticholinergic effects of TCAs are considered a medical emergency?

Study These Flashcards
A

constipation and urinary retention

20
Q

How long odes it take for TCAs to reach full effect?

21
Q

What are the adverse effects of TCAs?

Study These Flashcards
A
  1. orthostatic hypotension
  2. Dysrythmias
  3. MI
  4. Heart block
22
Q

Which medication class is very cardio toxic?

23
Q

What are the contraindications of TCAs?

Study These Flashcards
A
  1. Recent MI
  2. Narrow angle glaucoma
  3. Benign prostatic
  4. Hypertrophy
  5. seizures
  6. preggo
24
Q

What are the different MAOIs?

Study These Flashcards
A
  1. Phenelzine
  2. Tranylcypromine
  3. Isocarboxazid
  4. Selegiline
25
What can MAOIs cause?
HTN crisis
26
What are the symptoms of a HTN crisis?
1. Severe HA or blurry vision 2. chest pian 3. tachycardia 4. SOB 5. Diaphoresis 6. Anxiety 7. Mental status change 8. confusion N/V
27
If switching from SSRI to MAOI how long is the wash out period?
5 week cleanse
28
if switching from MAOI to SSRI how long is the cleanse?
14 days
29
What foods do you avoid when taking MAOIs?
tyramine foods need to be avoided **Will cause HTN if eaten**
30
What are the contraindications of MAOIs?
1. CVD 2. HTN 3. CHF 4. liver disease 5. recurrent ot severe HA 6. Recent surgery
31
Which antidepressant is mainly used for smoking cessation and prevention of seasonal depression?
Buproprion
32
What are the adverse effects of bupropion?
1. Appetite suppression 2. seizures
33
What medication targets suicide ideation?
Ketamine
34
How can Ketamine be administered?
IV and nasal
35
What are the side effects of ketamine?
increased BP, HR Disassociation
36
alternative treatments for depression
light therapy st johns wort

mental health (14 decks)

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