(III) Fastidious Gram Negative Rods (3) Bartonella spp.

Question 1

Characterize (1) : Bartonella henselae

Answer 1

Gram (-) rod

Question 2

What stain is used to visualize B. henselae?

Answer 2

Warthin-Starry silver stain

Question 3

ROT (route of transmission): B. henselae

Answer 3

Cat scratches

Question 4

What is the most distinctive symptom of Cat-Scratch Disease?

Answer 4

Axillary lymphadenopathy

(Note: Cat-Scratch Disease causes a granulomatous reaction)

Question 5

Does Cat-Scratch Disease occur in immunocompetent or immunocompromised individuals?

Answer 5

Competent

Question 6

Does Bacillary angiomatosis occur in immunocompetent or immunocompromised individuals?

Answer 6

Compromised

Question 7

What is the most distinctive symptom of Bacillary angiomatosis?

Answer 7

Raised red vascular lesions

Question 8

Treatment: Cat-Scratch Disease

Answer 8

Macrolide

Question 9

Treatment: Bacillary angiomatosis

Answer 9

(1) Doxycycline
(2) Macrolide

(Doxycycline is only indicated for bacillary angiomatosis, hence it being directly adjacent to the cat)

Question 10

Bartonella spp. infection

Transmission: […]

Clinical Presentation:
[…]

Diagnosis Serology, histology, culture

Answer 10

Bartonella spp. infection

Transmission: sandflies, louse borne, fleabite

Clinical Presentation:
- Trench fever
- Cat scratch disease (painful persistent regional lymphadenopathy)
- Aids-related vascular lesions (bacillary angiomatosis, bacillary peliosis, endocarditis)

Diagnosis Serology, histology, culture

Various vectors, basically.