(III) Fastidious Gram Negative Rods (5) Brucella spp.

Question 1

Characterize (2) : Brucella

Answer 1

(1) Gram (-) rod
(2) Facultative intracellular

Question 2

Reservoir: Brucella

Answer 2

Farm animals

Question 3

ROT: Brucella

Answer 3

(1) Unpasteurized dairy
(2) Direct contact

Question 4

Name 4 signs/symptoms of Brucellosis

Answer 4

(1) Anorexia
(2) Undulating fever
(3) Hepatosplenomegaly
(4) Osteomyelitis

Question 5

Treatment: Brucella

Answer 5

Doxycycline + Rifampin

Question 6

Is Rifampin used for treatment or prophylaxis of Brucellosis?

Answer 6

Treatment

Question 7

Brucella spp. infection

Transmission:
[…]

Clinical Presentation:
[…]

Answer 7

Brucella spp. infection

Transmission:
zoonotic - either
- direct contact with infected animal
- consumption of contaminated meat/milk/cheese
- inhalation of aerosols

Clinical Presentation:
Brucellosis (Maltese/undulating fever):
- PUO
- chronic brucellosis (low grade fever with malaise)
- bone and joint symptom (esp sacro-iliac joints)
- osteomyelitis
- endocarditis
**(associated with many other febrile diseases, but with emphasis on muscular pain and night sweats. The duration of the disease can vary from a few weeks to many months or even years.)
**BruCEllOsis