Furosemide (CARDIAC OR RESPIRATORY) Flashcards
What are the indications for furosemide
pulmonary oedema and/or respiratory distress due to acute heart failure
what is the pharmacokinetics for furosemide
administration: parental/enteral (including oral and IV)
distribution: plasma protein
metabolized: liver
excreted: urine
what is the pharmacodynamics for furosemide
furosemide is a potent diuretic that acts on the kidneys to increase water loss from body to increase the excretion of sodium and water by the kidneys
furosemide inhibits the kidney’s reabsorption from the proximal and distal tubules and the loop of henle.
This works by acting directly on the cells of the nephron and indirectly modifies the content of the renal filtrate
what are the contraindications for furosemide
reduced GCS with liver cirrhosis (liver scarring due to long-term liver damage)
cardiogenic shock (when heart can’t pump enough blood)
severe renal failure with anuria (no urine)
children under 18 years old
possible adverse effects of furosemide
hypotension
gi disturbances
what is the adult dosage of furosemide
IV—> 40mg (given as 20mg/2ml)
how is furosemide presented on the road
20mg in 2ml (injection)
50mg in 5ml (injection)
what does furosemide do
potent diuretic with a rapid onset (within 30 minutes) and has a short duration
what is the max dose for furosemide
40 milligrams (mg) meaning only 1 dose can be given
should furosemide be given quick or slow through IV (give the time)
SLOWLY (2 minutes)
when should you consider to give furosemide
when time to get to hospital is prolonged
what are the cautions of furosemide
hypokalaemia (low potassium) as can cause arrythmia
pregnancy
hypotension
How is furosemide presented on the road (HINT 2 ways)
20 milligram in 2ml injection ampoule
50 milligrams in 5ml injection ampoule
what is the route of administration for furosemide
IV
