Asprin (CARDIAC DRUG)

Question 1

what is the pharmacokinetics for asprin

Answer 1

administration: enteral
Distribution: plasma protein
metabolism: liver
excretion: urine

Question 2

What are the pharmacodynamics for aspirin

Answer 2

anti-platelet: prevents platelets to group together within the clotting process which prevents platelet plugs from growing or new ones from forming.

Meaning a reduction in clot formation

prevents synthesis of platelet aggregation (grouping) inhibitor prostaglandins which would cause pain swelling and inflammation.

Question 3

what are the indications for aspirin

Answer 3

clinical or ECG evidence showing MI or ischemia

suspected TIA including ALL of the following:
symptoms have FULLY resolved
Pt is NOT being conveyed to hospital
pt has been referred into local TIA pathway

Question 4

what are the contra indications for aspirin

Answer 4

known allergy or sensitivity to aspirin
children under 16
active gi bleeding
hemophilia or other clotting disorders
severe hepatic failure WITH jaundice

Question 5

how is aspirin presented on the road

Answer 5

300 milligram (mg) aspirin (acetylsalicylic acid)
in tablet form which can be chewable or dissolved

Question 6

what are the adverse effects caused by aspirin

Answer 6

GI bleeding
wheezing with asthma due to it the drug having NSAID properties

Question 7

what is the adult dosage for aspirin

Answer 7

300 milligram (mg) in tablet form

Question 8

what is the max dose for aspirin in adults?
What if the pt has already had below 300milligram (mg) of aspirin in the same day (UPDATED)

Answer 8

1 tablet (300 milligram (mg))
If the patient has had below 300 milligram (mg) of aspirin in that same day, the full 300 milligram (mg) should still be given.

If pt has had 300 milligram (mg) of aspirin that day DO NOT give anymore.

Question 9

why can aspirin not be given to children under 16

Answer 9

aspirin may cause Reye’s syndrome (this syndrome is rare and occurs in young children it damages their liver and brain)