Week 3 Pre-Learning: Bilirubin, Bile Flashcards

1
Q

What is bilirubin? (2)

A
  • macrophages in the spleen and liver break down old red blood cells
  • bilirubin is a byproduct of the destruction of aged red blood cells
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2
Q

Bilirubin is a key component of ___

A

bile

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3
Q

What is conjugated, or direct bilirubin? (2)

A
  • Once RBC are destroyed, they become bilirubin, which needs to be removed from the body
  • it needs to be processed (conjugated) by the liver, which makes it water soluble and allows it to be excreted in the bile
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4
Q

Unconjugated bilirubin is also called ____ or ____ bilrubin

A
  • direct
  • free
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5
Q

What occurs in the large intestine to bilirubin? (2)

A
  • bacteria converts bilirubin into stercobilinogen and urobilinogen
  • Stercobilinogen gives feces its brown colour
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6
Q

Unconjugated vs Conjugated bilirubin diagram

A
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7
Q

What is bile made up of? (5)

A
  • bile salts
  • cholesterol
  • bilirubin
  • electrolytes
  • water
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8
Q

What is bile required for? (2)

A
  • emulsification
  • absorption of fat in the intestinal tract
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