Week 3 Pre-Learning: Other Manifestations of Cirrhosis Flashcards

1
Q

Why does jaundice occur in cirrhosis?

A
  • Hepatic jaundice can occur due to damage of liver cells and intrahepatic cholestasis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Why do infections occur with cirrhosis?

A
  • Portal-systemic shunts (collateral circulation) created as a result of portal HTN allow ingested bacteria to bypass the liver
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hepatorenal syndrome may occur with cirrhosis. What is that? (2)

A
  • sudden decrease in urinary output
  • elevated BUN and creatinine levels
  • Increased urine osmolality
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hormonal imbalances may occur with cirrhosis. Why? (2)

A
  1. Impaired breakdown of steroid hormones (ex. aldosterone, estrogen, testosterone)
    - can cause water/Na+ retention, testicular atrophy, gynecomastia, amenorrhea, spider angiomas, palmar erythema. and abnormal hair growth
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drug toxicity may occur with cirrhosis. Why?

A
  • Impaired hepatocyte function can result in impaired clearance of drugs. This can cause elevated levels of drugs or metabolites in the blood, and can have toxic effects
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cirrhosis of the liver Body Diagram*

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly