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Clinical Chemistry II > Tumor Marker Quiz > Flashcards

Tumor Marker Quiz Flashcards

1
Q

Enzyme Tumors

A

PSA
THYMIDINE KINASE
ARYL SULFATASE b
Ck-BB

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2
Q

Hormone

A

Calcitonin
PRL
ACTH
hCG

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3
Q

Oncofetal antigen

A

AFP
CEA
Squamous cell antigen
Tennessee antige.

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4
Q

Carbohydrate marker

A

CA 125
Episialin
DU-PAN-2

CA-19

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5
Q

Non enzyme protein

A

C-peptide
IgG
B2-microglobulin
Preganancy specific antigen

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6
Q

Multiple myeloma

A

BJP

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7
Q

Hydatidiform mole

A

hCG

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8
Q

Liver CA

A

AFP

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9
Q

Intestinal CA

A

CEA

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10
Q

Prostatic CA

A

PSA

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11
Q

Aldolase, Alcohol Dehydrogenase, Hexokinase

A

Liver only

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12
Q

CA-12

A

Ovarian, endometrial

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13
Q

ACTH, Bombesin, Neurophysins

A

Small-cell lung cancers

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14
Q

PSA, CK-BB

A

Prostate

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15
Q

LDH, tdt, thymidine kinase

A

Leukemias

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16
Q

CA-15-3, CA549, MCA

A

Ovarian, Breast

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17
Q

Alkaline Phosphatase

A

Ovarian, Lung, Bone, Liver

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18
Q

CA-19-9, CA 19-5, CA 242, CA-50

A

Pancreatic, GIT

19
Q

hCG

A

Embyonal, choriocarcinomas

20
Q

CA-27, CA-29

A

Breast only

21
Q

Aryl sulfatase B

A

Colon, Breast

22
Q

Catecholamine metabolites

A
23
Q

Calcitonin

A

Medullary thyroid

24
Q

Tennessee antigen

A

Colon, GIT, gall bladder

25
Q

Amylase

A

Pancrease only

26
Q

Oncogene

A

N-Ras
K-ras, bcl-2
N-myc
c-erb B-2
c-abl/bcr
c-myc

27
Q

What are the potential uses of tumor markers in the clinical setting?

A

Screening in general population
Differential diagnosis in symptomatic patients Clinical staging of cancer

28
Q

N-ras

A

AML, NEUROBLASTOMA

29
Q

VHL

A

Kidney

30
Q

K-ras, bcl-2

A

Lymphoma, leukemia

31
Q

DCC, APC

A

colorectal

32
Q

N-myc

A

Nueroendocrine

33
Q

P16 E-cadheria, BRCA2, RB1

A

Breast

34
Q

c-erb B-2

A

breast, ovarian, GIT

35
Q

P53

A

breast, liver, bladder,sarcomas

36
Q

WT 1

A

Wilms tumor

37
Q

C-myc

A

c-myc T- & B-lymphoma, lung

38
Q

cdk a2

A

bladder, melanoma, glioblastoma

39
Q

Chronic myeloid leukemia (CML)

A

c-abl/bcr

40
Q

Chronic myeloid leukemia (CML)

A

meningioma, neurofibromatosis 2

41
Q

NF2

A

meningioma, neurofibromatosis 2

42
Q

RB1

A

retinoblastoma, osteosarcoma

43
Q

p16

A

bladder, melanoma, glioblastoma

Clinical Chemistry II (45 decks)

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