Lecture 22/23 Glycolysis & ETC Flashcards
Who discovered the Krebs cycle?
Sir Hans Krebs
The Krebs Cycle
the oxidation of Acetyl-CoA to produce some ATP and the reduced coenzymes NADH and FADH2
Bridge Step
pyruvic acid (from glycolyssi) is oxidized and decarboxylated
Products of the bridge step
NADH, CO2, and Acetyl CoA
Products of the krebs cycle
8 NADH, 2 FADH2, 2 ATP
1 NADH =
3 ATPs
1 FADHs =
2 ATPs
Electron Transport Chain
NADH and FADH2 transfer their electrons through a series of carrier molecules
Where does the ETC happen?
in the cell membrane of bacteria
Can prokaryotes only use oxygen as the final electron accpetor?
No!
Heme
iron-containing group that can alternate between Fe2+ and Fe3+
The two parts of the ETC
electron transport and chemiosmosis
What does electron transport involve?
electrons are transferred to a terminal electron acceptor via electron carriers with concurrent proton translocationW
What does chemiosmosis involve?
general term for the use of ion gradients to generate ATP, uses potential energy of an electrochemical gradient to phosphorylate ADP to ATP
Enzyme involved in the ETC
ATP synthase
