Multiple Sclerosis Flashcards

1
Q

what is multiple sclerosis

A

chronic autoimmune disease demyelinating CNS

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2
Q

types of multiple sclerosis

A

can be relapsing, progressive or both

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3
Q

what is active multiple sclerosis

A

2 relapses in past 2yr despite tx with interferon beta

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4
Q

aim of tx of multiple sclerosis

A

to manage symptoms

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5
Q

what are the symptoms of multiple sclerosis

A
  • spasticity
  • relapses
  • oscillopsia (objects vibrating)
  • mood alteration
  • fatigue
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6
Q

multiple sclerosis symptom

How to manage spasticity

A
  • baclofen
  • diazepam
  • tizanidine
  • dantrolene
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7
Q

multiple sclerosis symptom

how to manage relapses

A

methylprednisolone

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8
Q

multiple sclerosis symptom

how to manage mood alteration

A

amitriptylline

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9
Q

multiple sclerosis symptom

how to manage oscillopsia

A

gabapentin

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10
Q

multiple sclerosis symptom

how to manage fatigue

A

amantadine or fampride

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11
Q

what is the major s/e in baclofen

A

sedation and hypotonia (decreased muscle tone)

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12
Q

how to stop major s/e in baclofen

A

dose slowly

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