Nausea and Vomiting with cyototoxin Flashcards

1
Q

N+V types of symptoms

A

acute, delayed or anticipatory

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2
Q

which one(s) is more difficult to control = delayed, anticipatory and acute symptoms of N+V

A

delayed or anticipatory more difficult to control than acute

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3
Q

who experiences N+V more

RISK FACTORS

A
  • women
  • pt <50
  • anxiety
  • repeated exposure
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4
Q

drugs which cause mild N+V

A
  • fluorocuracil
  • exopuride
  • methotrexate
  • vinca alkaloids
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5
Q

drugs which cause moderate N+V

A
  • taxanes
  • doxorubicin
  • low cyclophsophamide doses
  • mitoxantrane
  • high methotrexate doses
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6
Q

drugs which cause severe N+V

A
  • cisplatin
  • dacarbazine
  • high cyclophosphamide doses
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7
Q

examples of drugs given to low risk and high risk pt

prevention of N+V acute symptoms

within 24hr of tx

A
  • low risk pt = dexamethasone, lorazepam
  • high risk pt = ondansetron, dexamethasone + aprepitant
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8
Q

examples of moderate and high emetogenic drugs

prevention of N+V delayed symptoms

start after 24hr

A
  • moderate emtogenic drugs = dexa + ondan
  • highly emetogenic drugs = dexa + aprepitant
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9
Q

prevention of N+V anticipatory symptoms

before tx

A

lorazepam

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