1st Generation AntiHistamines

Question 1

Diphenhydramine brand name

Answer 1

Benadryl

Question 2

Diphenydramine Indication

Answer 2

Relief of allergic Symptoms caused

by : Anaphylaxis, Sesonal Allerigic rhinitis, Allergic dermatoes

Question 3

Diphenydramine

Action

Answer 3

Antagonizes the effects of histamine at the H1-Receptor

Does not bind to or inactiviate histamine

Question 4

Diphenydramine

Side Effects/ Adverse

Answer 4

Drowsiness, Dizziness, Blurred vision, Hypotention, dry mouth, dry eyes, constipation, Dysuira ( urinary output disfunction), photosensitivity, wheezing

Question 5

Diphenydramine

contraindiction

Answer 5

• Hypersensitivity , Acute attacks of asthma,COPD, severe liver disease

Question 6

Diphenydramine

Nursing Consideration

Answer 6

• asses for signs of dysuria, retention, altered frequency,

- Asses cardiac and respriatory sounds

Question 7

Diphenydramine

Patient teaching

Answer 7

• Avoid driving / operating machineary ( medicine can cause drowsiness)
• Avoid Alcohol & other CNS Depressants

Question 8

Brompheniramine Tannate Indication

Answer 8

Combination Drug of Antihistamine & Decongestants.

- for allergic rhinitis ,common cold.

Question 9

Brompheniramine Tannate Action

Answer 9

antagonist of the H1 histamine receptors

Question 10

Brompheniamine Tannate Side Effects/ Adverse Side effects

Answer 10

Drowsiness, Dry mouth, Constipation , urinary rentention, insomina, nervousness

Question 11

Brompheniamine Tannate Contraindiction

Answer 11

Angle-closure glacoma, High blood pressure

Question 12

Brompheniamine Tannate Nursing consideration

Answer 12

• check for urinary rentention
• monitory signs for hypersenitivity
• access heart rate
• Access ECG

Question 13

Bromopheniamine Tannate Patient teaching

Answer 13

Advise patient about the risk of daytime drowsiness and decreased attention and mental focus.

Question 14

chlorpheniramine Indication

Answer 14

Relief of allergic symptoms caused by histamine release, including Nasal allergies, Allergic dermatoses.

Question 15

Chlorpheniramine

Action

Answer 15

Antagonizes the effects of histamine at H2 receptor sites; does not bind to or inactivate histamine.

Question 16

Chlorpheniramine

Side affects / Adverse effects

Answer 16

drowsiness, dizziness, excitation (in children). blurred vision. hypertension, arrhythmias, hypotension, palpitations. dry mouth, constipation, obstruction. retention, urinary hesitancy.

Question 17

Chlorpheniramine

Contraindication

Answer 17

-Closed Angle Glacuma, High blood pressure

Question 18

Chlorpheniramine

patient teaching

Answer 18

Advise patient about the risk of daytime drowsiness and decreased attention and mental focus.

Question 19

Clemastine indication

Answer 19

Relief of allergic symptoms caused by histamine release, including Allergic rhinitis, Urticaria.

Question 20

Clemastine Action

Answer 20

Antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamin

Question 21

Clemastine Side Effects

Answer 21

drowsiness, confusion, dizziness, paradoxical excitation (children). EENT: blurred vision. CV: hypertension, arrhythmias, hypotension, palpitations, tachycardia. GI: dry mouth, constipation, nausea, obstruction, vomiting. GU: urinary retention. Derm: rash. Resp: thick mucus.

Question 22

Clemastine contraindiction

Answer 22

Asthma, COPD, Closed Angle Glaucoma, Cardiac Disease

Question 23

Clemastine Nursing consideration

Answer 23

Monitor for drowsiness, poor coordination, or dizziness, especially in the older adult or debilitated. Supervision of ambulation may be warranted. Assess for symptomatic relief with use of the medication

Question 24

Clemastine Patient Teaching

Answer 24

• Advise patient about the risk of daytime drowsiness and decreased attention and mental focus.
• ## Advise patient to avoid alcohol and other CNS depressants because of the increased risk of sedation and adverse effects.

Question 25

Cyproheptadine Brand name

Answer 25

Periactin

Question 26

Cyproheptadine Indication

Answer 26

Relief of allergic symptoms caused by histamine release including Seasonal and perennial allergic rhinitis; Chronic urticaria, Cold urticaria

Question 27

Cyproheptadine Action

Answer 27

Antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamine. Also blocks the effects of serotonin, which may result in increased appetite.

Question 28

cyproheptadine | Side effects

Answer 28

drowsiness, excitation (increased in children). EENT: blurred vision. CV: arrhythmias, hypotension, palpitations. GI: dry mouth, constipation. GU: hesitancy, retention. Derm: photosensitivity, rashes. Misc: weight gain.

Question 29

Cyrproheptadine | Contradictions

Answer 29

- Overactive Thyorid Hormone | - High B.P

Question 30

Cyrproheptadine | Nursing Consideration

Answer 30

Assess exercise tolerance frequently (BP, heart rate, fatigue levels), and terminate exercise

Question 31

Cyropheptadine | Patient Teaching

Answer 31

- risk of daytime drowsiness and decreased attention and mental focus - Advise patient to avoid alcohol and other CNS depressants because of the increased risk of sedation and adverse effects. - instruct patient to report other troublesome side effects such as severe or prolonged skin rash, blurred vision, problems with urination, or GI problems

Question 32

Levocetrizine | Brand name

Answer 32

Xyzal

Question 33

Levocetrizine | Indication

Answer 33

Management of seasonal/perennial allergic rhinitis. Management of chronic idiopathic urticaria.

Question 34

Levocetrizine | Action

Answer 34

Antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamine

Question 35

Levocetrizine Side effects / Adverse

Answer 35

drowsiness, fatigue, weakness. dry mouth

Question 36

Levocetrizine Contraindiction

Answer 36

- Hypersenstvity | - End stage Renal Disease

Question 37

Levocetrizine | Nursing Consideration

Answer 37

guard against falls and trauma (hip fractures, head injury, and so forth). Implement fall-prevention strategies , especially in older adults or patients with excessive drowsiness, weakness, or fatigue

Question 38

Levocetrizine | Patient Teaching

Answer 38

- Day time drowsiness - Mindful of dry mouth - Avoid CNS depressants & Alcohol

Question 39

Azelastine | Indication

Answer 39

Management of the symptoms of seasonal allergic rhinitis in patients ≥5 yr. Management of vasomotor rhinitis in patients ≥12 yr.

Question 40

Azelastine | Action

Answer 40

Locally antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamine

Question 41

Azelastine Side effects / adverse

Answer 41

drowsiness, dizziness, dysesthesia, fatigue, headache. epistaxis, nasal burning, pharyngitis, sinusitis, sneezing. bitter taste, dry mouth, nausea. weight gain. myalgia

Question 42

Azelastine Contraindication

Answer 42

- Active & Inactive T.B - Herpes simplex infection of the eye -

Question 43

Azelastine | Nursing Considerations

Answer 43

- Assess dizziness and drowsiness that might affect gait, balance, and other functional activities - Assess any muscle pain to rule out musculoskeletal pathology

Question 44

Azelastine | Patient teaching

Answer 44

- day time drowsiness | - Avoid CNS depressants & Alcohol