2. Coronavirus Flashcards
(43 cards)
Major cause of coronavirus
travel
Coronavirus
- enveloped / non-enveloped?
- RNA / DNA virus?
- singe/double stranded?
enveloped
RNA virus
single-stranded
Coronavirus
Order:
Family:
Genera:
Order: Nidovirales
Family: Coronaviridae
Genera:
1) Alpha-CoV
2) Beta-CoV***
3) Delta-CoV
4) Gamma-CoV
Subgenus of SARS
Sarbecovirus
Subgenus of MERS
Merbecovirus
SARS-CoV
reported case: _____
deaths: _____
countries: _____
reported case: 8,096
deaths: 774 (~9.6% case fatality)
countries: 37
Where SARS-CoV originated
Guangdong Province, China
Time span of SARS-CoV
November 2002 – July 2003
Other term for SARS-CoV
“Infectious atypical pneumonia”
New coronavirus not previously endemic in humans
SARS-CoV
Cases of SARS-CoV had epidemiological links
to the ____-___ animal trade.
wild-game animal trade
Specimens are collected from
1)
2)
(also give scientific name)
- masked palm civet
(Paguma larvata) - raccoon dogs
(Nyctereutes procyonoides)
SARS CoV like virus with more than ___% nucleotide homology to the human SARS CoV
99% nucleotide homology
Middle East Respiratory Syndrome coronavirus (MERS)
reported case: _____
deaths: _____
countries: _____
reported case: “2,604”
deaths: “936” (~36% case fatality)
countries: “27”
Where MERS originated
Saudi Arabia
Time span of MERS
Sept 2012 - present
98-100% of ____ are (+) for MERS-CoV antibodies
camels
Incidence of MERS-CoV in humans is 15x higher in _______
camel shepherd
Incidence of MERS-CoV in humans is 23x higher in ____ __ than in general population.
slaughterhouse workers
Where COVID-19 originated
Wuhan, Hubei Province, China
Time span of COVID-19
Devember 2019 - present
was found to be an epidemiological link of the 100 initial patients exposed (COVID-19)
Wuhan Huanan Seafood Wholesale (Wet Market)
CoV attach to the host cell surface receptors via _____
spike protein (S)
______ is believed to play a crucial role in overcoming species barriers and accomplishing interspecies transmission from animals to human
S protein
