2.05 Fungal Infections Flashcards
(25 cards)
Causative agent of candidiasis
Candida albicans
Most frequent cause of human fungal infection
C. albicans
Predisposing factors for developing candidiasis
Prolonged antibiotic therapy Prolonged steroid administration Pregnancy Underlying disease Altered immunity
Candida albicans exists as a/an (intracellular/extracellular) parasite
Intracellular parasite
Chronic mucocutaneous candidiasis is usually seen in patients with
Patients with defects in cell-mediated immunity
Causative agent of Cryptococcosis
Cryptoccus neoformans
Presentation of cryptococcosis in healthy individuals
Meningoencephalitis
Presentation of cryptococcosis in immunocompromised individuals
Opportunistic infections
The polysaccharid capsule of C. neoformans has ___ which inhibits phagocytosis, leukocyte migration & inflammatory cell recruitment
Glucoronoxylomannin
Cryptococcus infects what organs
Lungs
CNS
Most common pathogenic species for humans in Aspergillosis
Aspergillus fumigatus
Infective stage of Aspergillus fumigatus
Conidia
Aspergillus fumigatus can be isolated from )))
Nuts and grains and decaying matter, soil, and air
Major portal of entry of A. fumigatus
Lung
Pathologic findings in Aspergillosis
Acute/narrow angle branching
Septate hyphae
Angioinvasive
Fungus appears as a protein body in the upper respiratory tract
Causative agent of Zygomycosis or Mucormycosis
bread mold fungi from the class Zygomycetes
Primary sites of involvement in Zygomycosis
Nasal sinuses
Lungs
GIT
Pathologic findgins in Zygomycosis
Broad, nonseptate hyphae
Right-angle branching
Angioinvasive
Yeasts form at __ temperature
body temperature
Molds form at ___ temperature
room temperature
Most common fungal endocarditis
Candida albicans
Cryptococcus neoformans is usually found in___ and infects people by __
Soil and bird droppings
Inhalation
Virulence factor of crytococcus
Glucoronoxylomannin
Laccase
Serine proteinase
Basement membrane proteins
Soap bubble lesions is found in __
cryptococcosis
