2.05 Parasitic Infections

Question 1

Which specie of plasmodium causes benign form of malaria

Answer 1

P. Vivax, ovale, and malariae

Question 2

Which species of plasmodium causes the severe form of malariae

Answer 2

P. Falciparum

Question 3

What is the infective stage of plasmodium to man

Answer 3

Sporozoites

Question 4

Diagnostic test for malaria

Answer 4

Blood smear

Question 5

Malignant cerebral malaria is causes by

Answer 5

Plasmodium falciparum

Question 6

Vector of malaria

Answer 6

Female anopheles mosquito

Question 7

Causative agent of babesiosis

Answer 7

Babesia microti and B. divergens.

Question 8

Histologic morphology of blood smear of patient with Babesiosis

Answer 8

resemble P. malaria ring stages but without hemozoin

Tetrads that form maltese crosses

Question 9

Mode of transmission of Leishmaniasis

Answer 9

Bite of infected sandfly

Question 10

Infective stage of Leshmania spp. to man

Answer 10

Promastigote

Question 11

Infective stage of Leshmania spp. to sandfly

Answer 11

Amastigote

Question 12

Virulence factor of promastigotes that promotes the adhesion of promastigotes to macrophages

Answer 12

Gp63

Question 13

Causative agent of visceral Leishmaniasis

Answer 13

L. donvani

Question 14

Presentation of visceral lieshmaniasis

Answer 14

Hepatosplenomegaly
lymphadenopathy
pancytopenia
fever, myalgia, weight loss
hyperpigmentation of skin (Kala-azar)

Question 15

Lesion in cutaneous lieshmaniasis

Answer 15

Tropical sore: Purple edematous plaque with central necrotic crust
Microscopic: granulomatous

Question 16

Causative agent of mucocutaneous lieshmaniasis

Answer 16

L. brazilensis

Question 17

Skin lesion in mucocutaneous lieshmaniasis

Answer 17

Espundia

Question 18

Causative agent of African Trypanosomiasis

Answer 18

Trypanosoma gambiense and T.rhodesiense

Question 19

African Trypanosomiasis is also known as

Answer 19

African Sleeping Sickness

Question 20

Lesion in African Trypanosomiasis

Answer 20

Large, rubbery, red chancre at site of insect bite

Question 21

The trypanosomes are found (inside or outside) the RBC

Answer 21

Outside the RBC

Question 22

Lieshmania is found (inside or outside) the RBC

Answer 22

Inside the RBC

Question 23

American Trypanosomiasis is also known as

Answer 23

Chagas Disease

Question 24

Causative agent of American Trypanosomiasis

Answer 24

Trypanosoma cruzi

Question 25

Skin lesion in American Trypanosomiasis

Answer 25

Chagoma

Question 26

Trypanosoma cruzi are transmitted via

Answer 26

Kissing bugs through their feces and non-intact skin

Question 27

Causative agent of strongyloidiasis

Answer 27

Strongyloides stercoralis

Question 28

Diagnostic tests for strongyloidiasis

Answer 28

Stool exam | Gastric lavage

Question 29

Causative agent of cystecerocis

Answer 29

Taneia solium

Question 30

MOT of cystecercosis

Answer 30

Ingestion of undercooked pork with cysterci | Ingestion of food or water contaminated with human feces

Question 31

Causative agent of Hydatid disease

Answer 31

Echinococcus granulosis

Question 32

MOT of causative agent of hydatid disease

Answer 32

Ingestion of food contaminated with eggs shed by dogs or foxes

Question 33

Hydatid disease most frequently invades the ___

Answer 33

Liver, aside from lungs and bones

Question 34

Causative agent of Trichinosis

Answer 34

Trichinella spiralis

Question 35

Mode of transmission of trichinella spiralis

Answer 35

Ingestion of undercooked meat from infected animals

Question 36

__ cells are muscle cells that have been parasitized by T. spiralis

Answer 36

Nurse cells

Question 37

S. japonicum is found in what part of the human host

Answer 37

Superior mesenteric vein

Question 38

S. mansoni is found in what part of the human host

Answer 38

inferior mesenteric vein

Question 39

S. hematobium is found in what part of the human host

Answer 39

Venous plexus of urinary bladder

Question 40

Liver cirrhosis in schistosomiasis is a result of

Answer 40

granuloma formation and fibrosis due to presence of eggs which elicit inflammatory responses

Question 41

Squamous cell carcinoma of the urinary bladder is associated with ___

Answer 41

S. hematobium

Question 42

S. hematobium infection presents with

Answer 42

hematuria and granulomatous disease of the urinary bladder (outlet obstruction)

Question 43

Causative agent of fliariasis

Answer 43

Wuchereria bacrofti and Brugia malayi

Question 44

Mosquito vector of Wuchereria bancrofti:

Answer 44

Culex, Anopheles, Mansonia & Coquillettidia

Question 45

Mosquito vector of Brugia malayi:

Answer 45

Culex, Mansonia, Anopheles

Question 46

Causative agent of Onchocerciasis

Answer 46

Onchocerca volvulus

Question 47

Onchocerciasis is transmitted via

Answer 47

the bite of black flies (Simullum sp)

Question 48

Important finding in onchocerciasis

Answer 48

``` Chronic dermatitis (leopard, lizard, elephant skin) Blindness Subcutaneous nodule (onchocercoma) ```

Question 49

Babesiosis is transmitted via

Answer 49

Tick bite (deer tick)

Question 50

Transmitter of african sleeping sickness

Answer 50

Tse tse fly