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1. Foundation > W2/L2: Intro to histology & blood > Flashcards

W2/L2: Intro to histology & blood Flashcards

1
Q

What charge does haematoxylin bind to?

A 
Negatively charged
(aka basophilic)
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2
Q

What sort of structures does haematoxylin stain?

A

The phosphate groups of DNA/RNA

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3
Q

What colour is haematoxylin?

A

Blue/purple

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4
Q

What charge does Eosin bind to?

A

Positively charged

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5
Q

What sort of structures does eosin stain?

A

Amino acids

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6
Q

What does amphophilic mean?

A

The cell binds both types of dyes

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7
Q

Approximately how much blood would a 70kg person have?

A

5L

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8
Q

What are the components of plasma?

A 
Water
Protein
Salts
Lipids
Sugar
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9
Q

What are the 3 main groups of proteins in plasma?

A

Coagulatory
Albumin
Globulins

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10
Q

What are erythrocytes

A

RBCs

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11
Q

About how many RBCs do we have per litre?

A

5 x 10^12 / L

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12
Q

What are the two groups of WBCs?

A

Granulocytes

Mononuclear leukocytes

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13
Q

Which cells are granulocytes?

A

Neutrophils
Eosinophils
Basophils

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14
Q

Which cells are mononuclear leukocytes?

A

Lymphocytes

Monocytes

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15
Q

Order the WBCs in descending concentration

A 
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
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16
Q

What is the haematocrit?

A

The proportion of blood volume that is RBCs

17
Q

What is normal haematocrit?

A

45%

18
Q

What are the key features of the RBC?

A

Biconcave disc

No nucleus or organelles

19
Q

What’s the life span of RBCs?

A

~120 days

20
Q

What’s a reticulocyte?

A

The immature form of RBCs first released into the blood

21
Q

What proportion of the circulating RBCs are reticulocytes?

A

About 1%

22
Q

What sort of things would cause an increased proportion of reticulocytes?

A

Haemorrhage or haemolysis

23
Q

What’s a normoblast?

A

The immature, nucleated RBC

24
Q

What are the characteristics of reticulocytes?

A

No nucleus

Some organelles

1. Foundation (31 decks)

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