Rheumatic fever

Question 1

Caused by

Answer 1

Group A beta hemolytic streptococci

Question 2

Complications early and late

Answer 2

Early lesion: mitral valve regurg
Early deaths due to myocarditis

Late lesion: mitral stenosis
Late sequelae: mitral>aortic»tricuspid (high pressure valve affected most)

Question 3

Finding

Answer 3

Aschoff bodies (granuloma with giant cell)
Anitschkow’s cells (activated histiocytes)
Elevated ASO

Question 4

Type of hypersensitivity

Answer 4

Type II, antibody to M protein

Question 5

Symptoms

Answer 5

FEVERSS;

Fever,
Erythema marginatum
Valvular damage (fibrosis and vegetation)
ESR increased
Red-hot joints (migratory polyarthritis)
Subcutaneous nodules
St. Vitus' dance (Sydenham's chorea)