Cholinomimetics(Muscarinic agonist)

Question 1

Mneumonic for Cholinomimetics

Answer 1

Become Muscarinic Pills

Question 2

Action of cholinomimetics

Answer 2

Direct-acting muscarinic cholinomimetic

Question 3

What receptor do they use to cause blood vessel dilation

Answer 3

M3

Question 4

Why don’t need nerve terminals?

Answer 4

Because they are direct acting

Question 5

What are drugs in this class(remember mneumonic)?

Answer 5

Bethanecol, Muscarine, pilocarpine, Cevimeline

Question 6

What is bethanecol used for?

Answer 6

B’s(bower and bladder post-operative relief

Question 7

What is pilocarpine used for?

Answer 7

Glaucoma; improves drainage from the canal of Schlemm. (Ac

Question 8

What is cevimeline used for?

Answer 8

Dry mouth(in e.g Sjorgren’s)

Question 9

Excessive Muscarinic stimulation is caused by?

Answer 9

AchE inhibitors

Question 10

What are the symptoms of excessive muscarinic stimulation

Answer 10

DUMBBELSS
Diarrhea
Urination
Miosis
Bradycardia
Bronchoconstriction
Excitation(CNS/muscle)
Lacrimation
Salivation
Sweating