Ergot alkaloids/Miscellanous Flashcards

1
Q

What are the receptors for -triptans?

A

5HT1B and 5HT1D agonist

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2
Q

What are -triptans used to treat?

A

Migraine

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3
Q

What is the mechanism of bromocriptine?

A

Dopamine agonist

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4
Q

What does bromocriptine treat?

A

Hyperprolactinemia

“Bros don’t like milk in their titties”

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5
Q

What does ergonovine treat?

A

Postpartum hemorrhage(Oxytocic)

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6
Q

What can you use to treat prodrome of migraine?

A

Ergotamine

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7
Q

What receptors doe ergotamine act on?

A

5HT1
5HT2
Alpha-adrenergic

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8
Q

What are the ergot alkaloids?

A

Ergotamine
Ergonovine
Bromocriptine
Methysergide

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9
Q

What is the mechanism of ergot alkaloids/

A

Agonist and antagonist actions at 5HT and alpha-adrenergic receptor

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10
Q

What are the important side effects of ergot alkaloids?

A

Powerful hallucinations

Smooth muscle contraction(vascular & uterine)

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