3. Brain communication and development Flashcards

(42 cards)

1
Q

What happens to ions to maintain resting potential?

A

Ion channels open to make the inside of the neuron more negative than the outside space

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2
Q

What are post synaptic potentials?

A

They nudge the resting state of membrane potential

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3
Q

What are two words to describe post synaptic potentials?

A

Rapid and decremental

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4
Q

What do post synaptic potentials do?

A

They futher polarise the neuron (hyperpolarise = more negative) which inhibits the likelihood of an action potential occuring

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5
Q

What does it mean if a neuron is hyperpolarised?

A

The inside of the cell is more negative so a bigger stimulus is needed to reach the threshold that the cell can fire at

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6
Q

What does it mean is a cell is depolarised?

A

It’s more positive which is excitatory and increases the chance of the cell generating an action potential

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7
Q

What chemical elements are inhibitory?

A

Potassium and Chlorine

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8
Q

What chemical element is excitatory?

A

Sodium

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9
Q

What is an action potential?

A

A rapid electrical signal that travels along the membrane allowing communication
an all or nothing phenomena, like firing a gun

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10
Q

What is the first step for an action potential to fire?

A

Depolarisation- sodium channels open, influx into cell

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11
Q

What is the second step for an action potential to fire?

A

Potassium channels open, potassium leaves

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12
Q

What is the third step for an action potential to fire?

A

Peak: sodium channels begin to close but potassium is still open

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13
Q

What is the fourth step for an action potential?

A

Repolarisation: sodium channels close, potassium still open

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14
Q

What is the final step for an action potential to fire?

A

Hyperpolarization: potassium channels close but some more leaks out the cell

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15
Q

Why are action potentials better than post-synaptic potentials?

A

Non-decremental

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16
Q

What is the cascading effect in action potentials?

A

They are able to transverse large distances because the depolarisation at the axon hillock leads to achievement of the threshold of excitation

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17
Q

What are the two types of synapses?

A

Electrical and chemical

18
Q

How do electrical synapses exist?

A

Gap between the pre and post synaptic neuron (gap junction) where the cytoplasm of the cells are connected permitting an electrical signal

19
Q

What are electrical synapses important for?

A

Reflexive processes and motor proceses

20
Q

What are some negatives of electrical synpases?

A

They are only a small signal so cannot bring a large response
They are also inflexible

21
Q

How do chemical synapses transmit signals ?

A

Vesicles in the terminal membrane contain neurotransmitters which are released into the synaptic cleft and bind to receptors in the post-synaptic neuron

22
Q

What are the two types of receptors called?

A

Direct (Ligand-gated ion channels) and indirect (G-protein-couple receptors)

23
Q

How do direct receptors work?

A

The neurotransmitter bind, the channel opens, ions flow through the membrane

24
Q

How do indirect receptors work?

A

Neurotransmitter binds, G-protein activates, sends intercellular message to an ion channel and ion channel opens

25
What are amino acids?
Molecular building of proteins from proteins we eat
26
What is an example of an excitatory amino acid?
Glutamate (released from amphetamines)
27
What is an example of an inhibitory amino acid?
GABA (released from alcohol)
28
What are neuropeptides?
Chains of amino acids
29
What are neuropeptides play a role in?
Appetite
30
What is enzymatic degradation?
After its action, an enzyme breaks down into parts and they cannot activate a receptor They can be re-uptaken, recycled and used again
31
What was the first observable part of the nervous system?
Neural plate- develops to form neural groove and neural tube
32
What are the three layers of the neural plate?
Endoderm, Medoderm and Ectoderm
33
What is migration?
once cells have been created they migrate to appropriate locations
34
What is differentiation in neuron cells?
Axon and dendrites will begin to grow
35
What is neuronal death?
More neurons than needed are produced so superfluous cells die This can be preprogrammed (apoptosis) or they can be rearranged (necrosis)
36
What is synaptogensis?
Formation of synaptic connections
37
How does synaptogensis change post-natally?
There is a rapid increase and this contributes to greater plasticity
38
How is myelination beneficial?
Increases speed of conduction and development
39
Where does myelination occur first post-natally?
Sensory areas, then motor areas, pre-frontal cortex development continues into adulthood
40
What is dendritic branching?
A rapid process where the generation of new dendrites leads to the creation of synpases
41
What is pruning?
'use it or lose it' carried out by microglia
42