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MSS > 3. Rheumatology and Immunology > Flashcards

3. Rheumatology and Immunology Flashcards

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1
Q

Specificity is the likelihood that an individual with a disease will test […].

A

negative

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2
Q

Ferritin and fibrinogen are examples of […] acute phase reactants.

A

positive

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3
Q

[…] antigen positivity is a specific marker for mixed connective tissue disease.

A

RNP

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4
Q

RNP antigen positivity is a specific marker for […] disease.

A

mixed connective tissue

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5
Q

[…] antigen is associated with systemic sclerosis.

A

scl-70

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6
Q

scl-70 antigen is associated with […].

A

systemic sclerosis

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7
Q

[…] antibodies are useful in diagnosing limited scleroderma.

A

Anti-centromere

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8
Q

Anti-centromere antibodies are useful in diagnosing […].

A

limited scleroderma

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9
Q

[…] antibodies attack citrulline residues that form in the post-translational modification of arginine.

A

anti-cyclic citrullinated peptide

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10
Q

anti-cyclic citrullinated peptide antibodies attack citrulline residues that form in the post-translational modification of […].

A

arginine

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11
Q

[…] is a more sensitive marker for inflammation compared to ESR.

A

CRP

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12
Q

CRP is a more sensitive marker for inflammation compared to […].

A

ESR

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13
Q

[…] presents with CREST syndrome: calcinosis, raynauds, esophageal dysmotility, sclerodactyly, and telangiectasia.

A

Limited scleroderma

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14
Q

Limited scleroderma presents with […] syndrome: calcinosis, raynauds, esophageal dysmotility, sclerodactyly, and telangiectasia.

A

CREST

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15
Q

Limited scleroderma presents with CREST syndrome: […].

A

calcinosis, raynauds, esophageal dysmotility, sclerodactyly, and telangiectasia

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16
Q

Inherited deficiencies in the […],[…], and […] complement proteins can predispose a person to develop SLE.

A

C1,C2,C4

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17
Q

Inherited deficiencies in the C1,C2, and C4 complement proteins can predispose a person to develop […].

A

SLE

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18
Q

Inflammatory disorder of joints usually cause this type of anemia:

A

anemia of chronic disease (normochromic normocytic)

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19
Q

The […] and […] are the joint sites most commonly affected by rheumatoid arthritis.

A

MCP, PIP

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20
Q

The […] joint at the base of the thumb is a common site of osteoarthritis.

A

carpometacarpal

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21
Q

The carpometacarpal joint at the base of the thumb is a common site of […].

A

osteoarthritis

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22
Q

[…] is joint pain without any deformities seen on exam and this is seen in non-articular joint disorders.

A

Arthralgia

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23
Q

Arthralgia is joint pain without any deformities seen on exam and this is seen in […] joint disorders.

A

non-articular

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24
Q

Acute […] is suggestive of gout, trauma, or infection.

Study These Flashcards
A

monoarthritis

25
Acute monoarthritis is suggestive of gout, [...], or infection.
trauma
26
[...] and Procainamide are two medications known to cause lupus-like syndrome.
Hydralazine
27
Hydralazine and [...] are two medications known to cause lupus-like syndrome.
Procainamide
28
Hydralazine and Procainamide are two medications known to cause [...].
lupus-like syndrome
29
The target structure in rheumatoid arthritis is the [...].
synovium
30
The [...] MCP's are the two more commonly involved MCP's in rheumatoid arthritis.
2nd and 3rd
31
The 2nd and 3rd MCP's are the two more commonly involved MCP's in [...].
rheumatoid arthritis
32
[...] is a common physical manifestation of rheumatoid arthritis.
Ulnar deviation
33
Ulnar deviation is a common physical manifestation of [...].
rheumatoid arthritis
34
[...] is the presence of rheumatoid nodules in the lungs causing rheumatoid lung disease.
Caplan's syndrome
35
Caplan's syndrome is the presence of rheumatoid nodules in the lungs causing [...].
rheumatoid lung disease
36
[...] occurs when patients with rheumatoid arthritis present with splenomegaly and a very low white blood cell count.
Felty syndrome
37
Felty syndrome occurs when patients with rheumatoid arthritis present with [...] and a very low white blood cell count.
splenomegaly
38
The gold standard for the treatment of rheumatoid arthritis is [...].
methotrexate
39
Prior to using [...] to treat rheumatoid arthritis, a PPD screening test must be done as there is a risk of disease reactivation.
TNF inhibitors
40
Prior to using TNF inhibitors to treat rheumatoid arthritis, a [...] test must be done as there is a risk of disease reactivation.
PPD screening
41
The [...] score is used to measure disease activity in rheumatoid arthritis.
das28
42
A das28 score of <2.6 implies [...] of rheumatoid arthritis.
remission
43
One of the ways that [...] affects the skin is by causing "weeping" of the tissues as well as the internal lining of organs and this is called serositis.
SLE
44
One of the ways that SLE affects the skin is by causing "weeping" of the tissues as well as the internal lining of organs and this is called [...].
serositis
45
[...] is the only drug that has been approves for targeted therapy for SLE.
Belimumab
46
Belimumab is the only drug that has been approves for targeted therapy for [...].
SLE
47
[...] works by blocking the BLyS protein thereby reducing B cell mediated immunity.
Belimumab
48
Belimumab works by blocking the [...] protein thereby reducing B cell mediated immunity.
BLyS
49
[...] and [...] antibodies are the two proteins to look for in association with SLE.
antidsDNA, anti-smith
50
antidsDNA and anti-smith antibodies are the two proteins to look for in association with [...].
SLE
51
[...] is marked by significant hypergammaglobulinemia or abnormal blood proteins.
Sjogren's syndrome
52
Sjogren's syndrome is marked by significant [...] or abnormal blood proteins.
hypergammaglobulinemia
53
A small subset of patients with [...] can go on to develop MALT lymphoma.
Sjogrens syndrome
54
A small subset of patients with Sjogrens syndrome can go on to develop [...].
MALT lymphoma
55
Class of drugs that should not be used in patients with sjogren's syndrome?
TNF-alpha inhibitors
56
[...] is the drug of choice for the sjogren patient with major organ involvement.
Azathioprine
57
Azathioprine is the drug of choice for the sjogren patient with major [...].
organ involvement
58
[...] is a pain syndrome that involves abnormal pain processing by the CNS.
Fibromyalgia

MSS (6 decks)

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