31. Psychotropic Agents

Question 1

One unique effect of alprazolam is its antidepressant effect

Answer 1

T

Question 2

Buspirone can be used on a PRN basis

Answer 2

F

Takes 2-4 weeks onset of action

Question 3

Doxepin has strong antipruritic effects as it is a very powerful H1 antihistamine

Answer 3

T

Question 4

Alprazolam is indicated for acute and self limited stress

Answer 4

T

Question 5

There is a 50 fold difference in trough blood levels among ind on same dose doxepin

Answer 5

T

Question 6

Doxepin is metabolize by cyp3a4

Answer 6

F

2D6

Question 7

Doxepin is associated with hypertension and weight loss

Answer 7

F
Hypotension
Weight gain
Cardiac conduction disturbance

Question 8

Which drugs require pre treatment ECG

Answer 8

Doxepin

Pimozide

Question 9

What are the discontinuation symptoms of stopping TCAs?

Answer 9

Uncomfortably vivid dreams
Transient dizziness
Nausea
Headache
Diaphoresis
Insomnia
Malaise

Question 10

Patients showing no improvement after 2 weeks should switch to another Ssri

Answer 10

F

6 weeks

Question 11

SSRIs have 5% incidence sexual difficulties

Answer 11

F

40%

Question 12

Switching to another class of antidepressants is appropriate when sexual adverse effects occur . Which class had less sexual dysfunction ?

Answer 12

Bupropion

Question 13

Discontinuation symptoms can occur with SSRIs and venlafaxine

Answer 13

T
Taper off slowly
Rather than abruptly

Question 14

Bupropion is not associated with seizure induction

Answer 14

F

Question 15

Long term Pimozide use is best avoided to minimisr risk of tardive dyskinesia

Answer 15

T

Question 16

Most common side effects of risperidone are anxiety dizziness and rhinitis

Answer 16

T

Question 17

There is a 50 fold difference in trough blood levels among ind on same dose doxepin

Answer 17

T

Question 18

Doxepin is metabolize by cyp3a4

Answer 18

F

2D6

Question 19

Doxepin is associated with hypertension and weight loss

Answer 19

F
Hypotension
Weight gain
Cardiac conduction disturbance

Question 20

Which drugs require pre treatment ECG

Answer 20

Doxepin

Pimozide

Question 21

What are the discontinuation symptoms of stopping TCAs?

Answer 21

Uncomfortably vivid dreams
Transient dizziness
Nausea
Headache
Diaphoresis
Insomnia
Malaise

MINDHUrT

Question 22

Patients showing no improvement after 2 weeks should switch to another Ssri

Answer 22

F

6 weeks

Question 23

SSRIs have 5% incidence sexual difficulties

Answer 23

F

40%

Question 24

Switching to another class of antidepressants is appropriate when sexual adverse effects occur . Which class had less sexual dysfunction ?

Answer 24

Bupropion

Question 25

Discontinuation symptoms can occur with SSRIs and venlafaxine

Answer 25

T Taper off slowly Rather than abruptly

Question 26

Bupropion is not associated with seizure induction

Answer 26

F

Question 27

Long term Pimozide use is best avoided to minimisr risk of tardive dyskinesia

Answer 27

T

Question 28

Most common side effects of risperidone are anxiety dizziness and rhinitis

Answer 28

T

Question 29

Most common ssri side effect is weight gain

Answer 29

F | Nausea and diarrhoea

Question 30

Pimozide is a potent centrally acting dopamine receptor agonist

Answer 30

F | Dopamine rec antagonist

Question 31

Venlafaxine has no sexual dysfunction

Answer 31

F | Less than SSRIs though

Question 32

Most common se of venlafaxine

Answer 32

Nervousness anxiety insomnia

Question 33

Bupropion is a weak inhibitor of dopamine re uptake

Answer 33

T

Question 34

Doxepin has a much higher affinity for histamine receptors than traditional antihistamines

Answer 34

T

Question 35

Night time dose of doxepin provides therapeutic benefit for 24h

Answer 35

T