3.2.4.4 - Humoral Immunity Flashcards Preview

MY biology > 3.2.4.4 - Humoral Immunity > Flashcards

Flashcards in 3.2.4.4 - Humoral Immunity Deck (10):
1

What is meant by 'humoral immunity'?

An immune response that involves the destruction of pathogens using antibodies.

2

How many different types of B-lymphocytes exist in the body?

10 million (approx) - each one has different shaped receptors that bind to specific antigens.

3

B-lymphocytes can develop into which type of cells after an immune response?

Plasma cells

Memory cells

4

Plasma cells develop from B-lymphocytes. What is their function?

They produce antibodies to destroy pathogens.

5

Memory cells can develop from B-lymphocytes. What is their function?

They are responsible for the secondary immune response.

If they encounter the same pathogen again they multiply rapidly and develop into plasma cells, which produce antibodies.

6

Describe the process of humoral immunity.

  1. Foreign antigen enters blood, initiating an immune response.
  2. A specific B-lymphocyte engulfs forein antigen via endocytosis and presents foreign antigens on its cell surface membrane.
  3. Th cell binds to and stimulates specfic B-lymphocyte to undergo mitosis (clonal selection).
  4. Cloned B-lymphocytes develop into plasma cells that produce monoclonal antibodies (primary response).
  5. Some B-lymphocytes become memory cells that circulate blood ready to develop into plasma cells upon a recurring infection (secondary response).

7

Describe how the presentation of a viral antigen leads to the secretion of antibody against viral antigens

T cells bind to the antigen (on APC)

T cells are activated in to T helper cells

T helper cells stimulate SPECIFIC B cells

B cells stimulated to divide by mitosis (clonal selection)

Forms plasma cells which release antibodies

8

What makes all antibodies unqiue?

Specific tertiary structure

Variable region will ONLY bind/complementary to one antigen

only forms antigen-antibody specific complexes with specific antigens

9

How is a secondary immune response different to a primary response

Secondary is

FASTER

GREATER concentration in antibodies produced

No LAG/Delay in antibody production

10

How is passive immunity different to active immunity

Passive is 

QUICKER

No MEMORY cells produced