3.2.4.2 - Phagocytosis Flashcards Preview

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Flashcards in 3.2.4.2 - Phagocytosis Deck (9):
1

How do phagocytes protect against pathogens, toxins, cancer cells or foreign tissues?

  1. The phagocyte is attracted by chemical products of the non-self material.
  2. The phagocyte has receptors that bind to the non self antigens of the material.
  3. The phagocyte engulfs the material (phagocytosis) and a phagosome is formed.
  4. A lysosome merges with the phagosome and lysozymes digest the material.
  5. Material debris is absorbed by the phagocyte. Antigens are presented on the surface of the phagocyte.

2

What is phagocytosis?

When foreign material is ingested by a phagocyte to form a phagosome.

3

T-Lymphocytes can be one of 2 types. What are they?

T-helper lymphocytes (Th)

Cytotoxic T-Lymphocytes (Tc)

4

Identify the 2 types of white blood cell.

Phagocytes (non-specific)

Lymphocytes (specific)

5

What are lysozymes?

Hydrolytic enzymes found inside lysosomes that digest foreign material.

6

What is a phagosome?

A vesicle containing foreign material within a phagocyte that is formed during phagocytosis.

7

Is phagocytosis a specific or a non-specific response to a non-self antigen?

Non-specific

8

Are Phagocytes 'antigen presenting cells'?

Yes - they present foreign antigens on their surface after engulfing a foreign material.

9

Describe how phagocytosis of a virus leads to presentation of its antigens

Phagosome FUSES with lysosome

lysosome contains lyzozymes which destroy virus]

antigen displayed on cell MEMBRANE of phagocyte (APC)