3.3 Study Guide Flashcards
similarities in amino acid structure
amino acid structures are all the same.
differences in amino acid structure
Primary Structure
order of amino acids
covalent bonds (formed by dehydration synthesis)
sequence determined by DNA
sequence determines final shape
Secondary Structure
small sections of folding
hydrogen bonds between carboxyls and amines of amino acids
combinations of a-helix and B pleated sheet
Tertiary Structure
Final 3D shape of single polypeptide
interactions between side chains
hydrophobic, acids and basics, cysteines, hydrophilic
Quaternary Structure
more than one polypeptide chain bonded together
Protein Denaturation
unfolding a protein
conditions that disrupt hydrogen and ionic bonds:
temperature
pH
salinity
Why and how would the structure and function of a protein change if a hydrophobic amino acid was substituted for a hydrophilic one?
