Neisseria

Question 0

N. meningitidis and N. gonorrhoeae Which one is more fastidious?

Answer 0

N. gonorrhoeae

Question 1

Structural elements of N. meningitidis and N. gonorrhoeae are same except that one of then has a polysaccharide capsule external to the cell wall. Which one?

Answer 1

N. meningitidis

Question 2

N. meningitidis serogroup __ causes widespread epidemics

Answer 2

A

Question 3

Serogroups of N.meningitidis are based on 
A. Outer membrane proteins
B. Polysaccharide capsule
C. Both of the above
D. None of the above

Answer 3

Serogroups are based on OMP’s and polysaccharide capsule

Answer: C

Question 4

False about N.meningitidis
A.Transmission by inhalation of aerosolized respiratory droplets
B. Infection is highest among infants
C. zoonotic disease happens more often because of this bacteria
D. None of those mentioned

Answer 4

C

Human: only natural host

Question 5

Which is not a virulence factor of N.meningitidis?
A. Capsule
B. Lipooligosaccharide
C. IgE protease
D. Outer membrane proteins

Answer 5

C

IgA dapat

Question 6

A.enters epithelium through membrane-bound vesicles
B.Pili attaches to CD46 protein of epithelial cells
C.damages cell by releasing endotoxin, travels through cell
D.exits cell to bloodstream
E. Bacteremia and invasion of CNS

Arrange steps in pathogenesis of N.meningitidis

Answer 6

B A C D E

Question 7

N.meningitidis grows in the ff except
A. Blood Agar Plate
B. Chocolate Agar
C. Bordet - Gengou Medium
D. None of the above

Answer 7

C

Question 8

First choice treatment drug for N.meningitidis

Answer 8

Penicillin

Question 9

Prophylaxis antibiotics for N.meningitidis

Answer 9

Rifampin, Ciprofloxacin

Question 10

Transmission of N.gonorrheae

Answer 10

Sexually transmitted

Question 11

Neisseria stick to mucous secretions and non-ciliated cells by their __ and __

Answer 11

Neisseria stick to mucous secretions and non-ciliated cells by their pili and Opa proteins

Question 12

___ of pili, Opa proteins and LOS enables gonococci to escape immune surveillance

Answer 12

Antigenic variation of pili, Opa proteins and LOS enables gonococci to escape immune surveillance

Question 13

False about N.gonorrheae
A.Anaerobic
B.Converts glucose to acetic acid
C.Capnophilic-
D.Require iron and nitrogen for growth -

Answer 13

A

aerobic dapat

Question 14

N.gonorrheae is said to be auxotrophic. What does this mean?

Answer 14

require one or more substances for growth

Question 15

Pathogenesis of N.gonorrheae: fill in the blanks

Initial attachment mediated by ___ Tighter attachment mediated by ___

Answer 15

Pili

Opa proteins

Question 16

__ trigger signaling cascade to induce phagocytosis of bacterial cell
A. Pili
B. Lipopolysaccharide
C. Opa proteins

Answer 16

C

Question 17

Ingestion and transport through epithelium is ___ to that of meningococci
A. Similar
B. Different
C. Varied

Answer 17

A

Question 18

What is parasite-mediated endocytosis?

Answer 18

Microbe tells microvilli via signals to phagocytose the said bacteria

Question 19

Mechanism of N.gonorrheae that downplays complement activation and makes it act like capsule

Answer 19

LOS Sialyation